Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease (Q47198022)

11 January 2018

title

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease (English)

1 reference

11 January 2018

V Stambolic

0 references

M S Tsao

1 reference

11 January 2018

author name string

S A Backman

1 reference

11 January 2018

A Suzuki

1 reference

11 January 2018

J Haight

1 reference

11 January 2018

A Elia

1 reference

11 January 2018

J Pretorius

1 reference

11 January 2018

P Shannon

1 reference

11 January 2018

B Bolon

1 reference

11 January 2018

G O Ivy

1 reference

11 January 2018

T W Mak

1 reference

11 January 2018

language of work or name

English

0 references

publication date

1 December 2001

1 reference

11 January 2018

published in

Nature Genetics

1 reference

11 January 2018

volume

1 reference

11 January 2018

issue

1 reference

11 January 2018

page(s)

396-403

1 reference

11 January 2018

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

cites work

1 reference

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

7 January 2021

PTEN: life as a tumor suppressor

1 reference

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

7 January 2021

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

7 January 2021

Germline mutations in PTEN are present in Bannayan-Zonana syndrome

1 reference

7 January 2021

Germline PTEN mutations in Cowden syndrome-like families.

1 reference

7 January 2021

PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome

1 reference

7 January 2021

PTEN and inherited hamartoma-cancer syndromes

1 reference

7 January 2021

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

1 reference

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

7 January 2021

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

1 reference

7 January 2021

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

7 January 2021

A role for nuclear PTEN in neuronal differentiation.

1 reference

7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

7 January 2021

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

1 reference

7 January 2021

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

7 January 2021

PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1

1 reference

7 January 2021

A novel monoclonal antibody specific for the N-terminal end of GAD65.

1 reference

7 January 2021

In situ hybridization to localize mRNA encoding the neurotransmitter synthetic enzyme glutamate decarboxylase in mouse cerebellum

1 reference

7 January 2021

Astrocyte responses to CNS injury

1 reference

7 January 2021

GABAA receptor antisense epilepsy: histological changes following infusion of antisense oligodeoxynucleotide to GABAA receptor gamma 2 subunit into rat hippocampus.

1 reference

7 January 2021

Activation of astrocytes during epileptogenesis in the absence of neuronal degeneration

1 reference

7 January 2021

Cellular survival: a play in three Akts

1 reference

7 January 2021

Modulation of cellular apoptotic potential: contributions to oncogenesis

1 reference

7 January 2021

The cells and molecules that make a cerebellum.

1 reference

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

7 January 2021

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

1 reference

7 January 2021

Postnatal maturation of rat Purkinje cells cultivated in the absence of two afferent systems: An ultrastructural study

1 reference

7 January 2021

Development of Purkinje cells in absence of climbing fibers

1 reference

7 January 2021

Granule neuron regulation of Purkinje cell development: striking a balance between neurotrophin and glutamate signaling.

1 reference

7 January 2021

The anatomy of the cerebellum

1 reference

7 January 2021

Association of Lhermitte-Duclos and Cowden disease: report of a new case and review of the literature.

1 reference

7 January 2021

Dysplastic gangliocytoma of cerebellum in a newborn. Case report

1 reference

7 January 2021

Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis

1 reference

7 January 2021

Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes

1 reference

7 January 2021

Proteus syndrome: diagnostic criteria, differential diagnosis, and patient evaluation

1 reference

7 January 2021

The radiological features of hemimegalencephaly including three cases associated with proteus syndrome

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG782

1 reference

11 January 2018

1 reference

11 January 2018