Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop. (Q47137624)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29169370%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop (English)

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4 April 2020

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neoplastic stem cells

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29169370%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Bhushan Thakur

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4 April 2020

publication date

23 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29169370%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental & Clinical Cancer Research

4 April 2020

published in

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4 April 2020

volume

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4 April 2020

issue

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4 April 2020

page(s)

164

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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

4 April 2020

cites work

1 reference

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Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention

23 May 2018

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An active IGF-1R-AKT signaling imparts functional heterogeneity in ovarian CSC population

23 May 2018

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Overexpression of β-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma

23 May 2018

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p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance

23 May 2018

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The PI3K/AKT Pathway as a Target for Cancer Treatment

23 May 2018

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Differential activation of NF-κB signaling is associated with platinum and taxane resistance in MyD88 deficient epithelial ovarian cancer cells.

23 May 2018

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NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC).

23 May 2018

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Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells

23 May 2018

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23 May 2018

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Cancer drug resistance: an evolving paradigm

23 May 2018

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The complexity of NF-κB signaling in inflammation and cancer

23 May 2018

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Targeting nuclear factor-kappa B to overcome resistance to chemotherapy.

23 May 2018

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Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

23 May 2018

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Non-invasive imaging of phosphoinositide-3-kinase-catalytic-subunit-alpha (PIK3CA) promoter modulation in small animal models

23 May 2018

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Mechanisms of chemoresistance in cancer stem cells

23 May 2018

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In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival.

23 May 2018

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Involvement of NF-κB activation in the cisplatin resistance of human epidermoid carcinoma KCP-4 cells

23 May 2018

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Cancer stem cells: in the line of fire

23 May 2018

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Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells

23 May 2018

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Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion

23 May 2018

1 reference

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Regulation of phosphoinositide 3-kinase expression in health and disease

23 May 2018

1 reference

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Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

23 May 2018

1 reference

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Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5701448

Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5701448

Cellular processing of platinum anticancer drugs

23 May 2018

1 reference

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Cisplatin resistance and transcription factors

23 May 2018

1 reference

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Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

23 May 2018

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Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro.

23 May 2018

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Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

23 May 2018

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Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference

23 May 2018

1 reference

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DNA-bound transcription factor complexes analysed by mass-spectrometry: binding of novel proteins to the human c-fos SRE and related sequences

23 May 2018

1 reference

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PIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients.

23 May 2018

1 reference

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PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells.

23 May 2018

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Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5701448

15 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/29169370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13046-017-0636-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29169370%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 April 2020

0 references

1 reference

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4 April 2020

PubMed publication ID

29169370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29169370%20AND%20SRC:MED&resulttype=core&format=json