The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation (Q47070662)

5 January 2018

title

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation (English)

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5 January 2018

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GOA release 2020-03-11

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5 January 2018

Jessica E Treisman

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5 January 2018

author name string

Ito N

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5 January 2018

Dickson BJ

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5 January 2018

Hariharan IK

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5 January 2018

language of work or name

English

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publication date

1 May 2001

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5 January 2018

published in

Cell

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5 January 2018

volume

105

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5 January 2018

issue

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5 January 2018

page(s)

345-355

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5 January 2018

Roughex mediates G(1) arrest through a physical association with cyclin A.

cites work

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7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

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7 January 2021

The Drosophila cyclin D-Cdk4 complex promotes cellular growth

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7 January 2021

Uncoupling cell fate determination from patterned cell division in the Drosophila eye.

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7 January 2021

From small flies come big discoveries about size control

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7 January 2021

Morphogenetic mutants detected in mitotic recombination clones

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7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

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7 January 2021

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

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7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

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7 January 2021

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Drosophila myc regulates cellular growth during development.

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7 January 2021

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

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7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

The roles of Drosophila cyclins A and B in mitotic control

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7 January 2021

Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

The TSC1 gene product, hamartin, negatively regulates cell proliferation

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Drosophila S6 kinase: a regulator of cell size

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Coordination of growth and cell division in the Drosophila wing

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Ras1 promotes cellular growth in the Drosophila wing

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Characterization and spatial distribution of the ELAV protein duringDrosophila melanogaster development

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Genetic control of cell size

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

The genetic basis of tuberous sclerosis.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900332-4

7 January 2021

10.1016/S0092-8674(01)00332-4

Identifiers

DOI

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5 January 2018

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5 January 2018