A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction (Q46914785)

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scientific article published on 5 November 2007

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English	A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction	scientific article published on 5 November 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17982471

A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction (English)

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17982471

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Maik Hüttemann

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Maik Hüttemann

6

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J Catharina Duvigneau

1

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Christina Piskernik

2

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Susanne Haindl

3

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Burkhard Kloesch

4

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Romana T Hartl

5

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Icksoo Lee

7

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Thomas Ebel

8

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Rudolf Moldzio

9

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Manfred Gemeiner

10

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Heinz Redl

11

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Andrey V Kozlov

12

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26 December 2017

http://europepmc.org/abstract/MED/17982471

publication date

5 November 2007

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26 December 2017

http://europepmc.org/abstract/MED/17982471

Laboratory Investigation

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26 December 2017

http://europepmc.org/abstract/MED/17982471

88

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26 December 2017

http://europepmc.org/abstract/MED/17982471

1

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26 December 2017

http://europepmc.org/abstract/MED/17982471

70-77

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17982471

Deferoxamine administration in septic animals: improved survival and altered apoptotic gene expression

1 reference

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Treatment with N-acetylcysteine plus deferoxamine protects rats against oxidative stress and improves survival in sepsis

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Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat.

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Modification of iron regulation by the inflammatory response.

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Role of metals in oxygen radical reactions

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Iron and infection: the heart of the matter

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21 January 2018

Oxidative metabolism in sepsis and sepsis syndrome

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Mitochondrial death in sepsis: a failed concept

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Reactive oxygen species produced by liver mitochondria of rats in sepsis.

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Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity

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Abnormal permeability of inner and outer mitochondrial membranes contributes independently to mitochondrial dysfunction in the liver during acute endotoxemia

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Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation

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Mitochondrial dysfunction in sepsis

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Protective effects of early treatment with propofol on endotoxin-induced acute lung injury in rats

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Delay in processing porcine whole blood affects cytokine expression

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Ischemia-reperfusion of rat liver modulates hepcidin in vivo expression

1 reference

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Intracellular free iron in liver tissue and liver homogenate: studies with electron paramagnetic resonance on the formation of paramagnetic complexes with desferal and nitric oxide

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

21 January 2018

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

21 January 2018

Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production.

1 reference

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21 January 2018

Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

21 January 2018

Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.

1 reference

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21 January 2018

Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney

1 reference

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Heme oxygenase-1 mediates up-regulation of adhesion molecule expression induced by peroxynitrite in endothelial cells

1 reference

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21 January 2018

Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential.

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21 January 2018

Outcome of patients with sepsis and septic shock after ICU treatment

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7 January 2021

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Deferoxamine reduces tissue injury and lethality in LPS-treated mice

1 reference

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7 January 2021

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Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS

1 reference

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7 January 2021

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Iron toxicity and chelation therapy

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

7 January 2021

based on heuristic

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Mechanism of iron toxicity.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

7 January 2021

based on heuristic

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Oxidative Metabolism in Rat Hepatocytes and Mitochondria during Sepsis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

7 January 2021

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Opposite effects of endotoxin on mitochondrial and endoplasmic reticulum functions

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https://api.crossref.org/works/10.1038%2FLABINVEST.3700691

7 January 2021

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Overexpression of CYP3A aggravates endotoxin-induced liver injury in hypophysectomized female rats

1 reference

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7 January 2021

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H(2)O(2) detection from intact mitochondria as a measure for one-electron reduction of dioxygen requires a non-invasive assay system

1 reference

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7 January 2021

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Electron paramagnetic resonance characterization of rat neuronal nitric oxide production ex vivo

1 reference

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Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron.

1 reference

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Pathophysiology of iron toxicity.

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Nitric-oxide-mediated activation of iron-regulatory protein controls hepatic iron metabolism during acute inflammation

1 reference

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7 January 2021

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Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.

1 reference

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7 January 2021

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Identifiers

10.1038/LABINVEST.3700691

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17982471

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17982471

ResearchGate publication ID

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