Prediction of cytochrome p450-mediated hepatic drug clearance in neonates, infants and children : how accurate are available scaling methods? (Q46906656)

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scientific article published in January 2006

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English	Prediction of cytochrome p450-mediated hepatic drug clearance in neonates, infants and children : how accurate are available scaling methods?	scientific article published in January 2006

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

Prediction of cytochrome p450-mediated hepatic drug clearance in neonates, infants and children : how accurate are available scaling methods? (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

author name string

Sven Björkman

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

publication date

1 January 2006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

45

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

1-11

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

Alfentanil pharmacokinetics in cardiac surgical patients

1 reference

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21 January 2018

Population pharmacokinetics and metabolism of midazolam in pediatric intensive care patients.

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Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants

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12 December 2020

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How important are gender differences in pharmacokinetics?

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Population pharmacokinetics of alfentanil: the average dose-plasma concentration relationship and interindividual variability in patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16430308

12 December 2020

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The disposition of alfentanil in neonates with respiratory distress

1 reference

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12 December 2020

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Expression of CYP2D6 in developing human liver

1 reference

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12 December 2020

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Expression of CYP3A in the Human Liver — Evidence that the Shift between CYP3A7 and CYP3A4 Occurs Immediately After Birth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16430308

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A pilot evaluation of alfentanil-induced miosis as a noninvasive probe for hepatic cytochrome P450 3A4 (CYP3A4) activity in humans

1 reference

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Drug metabolism and disposition in children

1 reference

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Dose estimation for children

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Pharmacokinetics of Drugs Used in Critically Ill Adults

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Pharmacokinetics of the infusion of alfentanil in man.

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A size standard for pharmacokinetics.

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Ontogeny of hepatic and renal systemic clearance pathways in infants: part II.

1 reference

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Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.

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Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam

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Effect of age, gender, and obesity on midazolam kinetics.

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Role of P-glycoprotein in pharmacokinetics: clinical implications

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Alfentanil kinetics in the elderly

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Influence of age on the pharmacokinetics of alfentanil. Gender dependence

1 reference

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Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16430308

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Protein binding predictions in infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16430308

12 December 2020

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Population pharmacokinetics of midazolam in neonates.

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Decreased fentanyl and alfentanil dose requirements with age. A simultaneous pharmacokinetic and pharmacodynamic evaluation

1 reference

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Size, myths and the clinical pharmacokinetics of analgesia in paediatric patients.

1 reference

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The pharmacokinetics of alfentanil in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/16430308

12 December 2020

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A pharmacokinetic study of midazolam in paediatric patients undergoing cardiac surgery

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Developmental expression of human hepatic CYP2C9 and CYP2C19.

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Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

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https://pubmed.ncbi.nlm.nih.gov/16430308

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Age-dependent cyclosporine: pharmacokinetics in marrow transplant recipients

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Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein

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Sex, age and alfentanil pharmacokinetics

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Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

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Blood cyclosporine pharmacokinetics in patients undergoing marrow transplantation. Influence of age, obesity, and hematocrit

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Limited contribution of CYP3A5 to the hepatic 6beta-hydroxylation of testosterone

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Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period

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Pharmacokinetics of midazolam in critically ill neonates

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Disposition and miotic effects of oral alfentanil: a potential noninvasive probe for first-pass cytochrome P4503A activity

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Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.

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Developmental expression of the major human hepatic CYP3A enzymes

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Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model

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Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions

1 reference

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200645010-00001

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16430308

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