Glatiramer Acetate Treatment Directly Targets CD11b+Ly6G− Monocytes and Enhances the Suppression of Autoreactive T cells in Experimental Autoimmune Encephalomyelitis (Q46858374)

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scientific article published on September 1, 2011

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English	Glatiramer Acetate Treatment Directly Targets CD11b+Ly6G− Monocytes and Enhances the Suppression of Autoreactive T cells in Experimental Autoimmune Encephalomyelitis	scientific article published on September 1, 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

Glatiramer acetate treatment directly targets CD11b(+)Ly6G(-) monocytes and enhances the suppression of autoreactive T cells in experimental autoimmune encephalomyelitis (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

Glatiramer Acetate Treatment Directly Targets CD11b+Ly6G− Monocytes and Enhances the Suppression of Autoreactive T cells in Experimental Autoimmune Encephalomyelitis (English)

1 reference

10.1111/J.1365-3083.2011.02575.X

https://api.crossref.org/works/10.1111/J.1365-3083.2011.02575.X

2 December 2024

2

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C. Y. Slaney

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595733

2 December 2024

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A. Toker

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595733

2 December 2024

B. T. Bäckström

3

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2 December 2024

J. L. Harper

4

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21595733

2 December 2024

publication date

1 September 2011

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

September 2011

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21595733

2 December 2024

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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-3083.2011.02575.x

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595733

2 December 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-3083.2011.02575.x

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10.1111/J.1365-3083.2011.02575.X

https://api.crossref.org/works/10.1111/J.1365-3083.2011.02575.X

2 December 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-3083.2011.02575.x

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10.1111/J.1365-3083.2011.02575.X

https://api.crossref.org/works/10.1111/J.1365-3083.2011.02575.X

2 December 2024

Scandinavian Journal of Immunology

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

74

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Europe PubMed Central

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25 December 2017

http://europepmc.org/abstract/MED/21595733

3

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

235-243

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

The origin and application of experimental autoimmune encephalomyelitis

1 reference

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Multiple sclerosis: a battle between destruction and repair

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Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

1 reference

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21 January 2018

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

1 reference

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21 January 2018

Mechanisms of action of glatiramer acetate in multiple sclerosis

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Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

1 reference

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21 January 2018

Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

1 reference

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21 January 2018

Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

1 reference

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21 January 2018

Glatiramer acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients

1 reference

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21 January 2018

Neurogenesis and neuroprotection in the CNS--fundamental elements in the effect of Glatiramer acetate on treatment of autoimmune neurological disorders

1 reference

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21 January 2018

Copolymer 1 acts against the immunodominant epitope 82-100 of myelin basic protein by T cell receptor antagonism in addition to major histocompatibility complex blocking

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Glatiramer Acetate (Copolymer-1, Copaxone) Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells

1 reference

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21 January 2018

Induction of IL-10 in rat peritoneal macrophages and dendritic cells by glatiramer acetate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

1 reference

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21 January 2018

Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis.

1 reference

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21 January 2018

A chimeric T cell receptor with super-signaling properties

1 reference

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21 January 2018

Axonal damage is reduced following glatiramer acetate treatment in C57/bl mice with chronic-induced experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

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21 January 2018

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Partial depletion of CD69low-expressing natural regulatory T cells with the anti-CD25 monoclonal antibody PC61.

1 reference

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21 January 2018

Glatiramer acetate and IFN-beta act on dendritic cells in multiple sclerosis

1 reference

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21 January 2018

Glatiramer acetate blocks interleukin-1-dependent nuclear factor-kappaB activation and RANTES expression in human U-251 MG astroglial cells

1 reference

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21 January 2018

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

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21 January 2018

CD11b+ monocytes abrogate Th17 CD4+ T cell-mediated experimental autoimmune myocarditis

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21 January 2018

Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2011.02575.X

21 January 2018

Structural insight into the function of myelin basic protein as a ligand for integrin alpha M beta 2.

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21 January 2018

beta2-integrins in demyelinating disease: not adhering to the paradigm

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Immunology of multiple sclerosis

1

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2 December 2024

Naïve blood monocytes suppress T‐cell function. A possible mechanism for protection from autoimmunity

15

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CD4(+)CD25(+) regulatory T cells contribute to the therapeutic effects of glatiramer acetate in experimental autoimmune encephalomyelitis

25

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Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells

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Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion

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CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

34

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Identifiers

10.1111/J.1365-3083.2011.02575.X

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/21595733

ResearchGate publication ID

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