Effects of permeability transition inhibition and decrease in cytochrome c content on doxorubicin toxicity in K562 cells (Q46838128)

25 December 2017

title

Effects of permeability transition inhibition and decrease in cytochrome c content on doxorubicin toxicity in K562 cells (English)

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25 December 2017

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25 December 2017

author name string

De Oliveira F

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25 December 2017

Chauvin C

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25 December 2017

Ronot X

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25 December 2017

Mousseau M

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25 December 2017

Leverve X

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25 December 2017

language of work or name

English

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publication date

1 April 2006

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25 December 2017

published in

Oncogene

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25 December 2017

volume

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25 December 2017

issue

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25 December 2017

page(s)

2646-2655

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25 December 2017

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

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Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

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Induction of chemoresistance in HL-60 cells concomitantly causes a resistance to apoptosis and the synthesis of P-glycoprotein

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Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells

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Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]

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The Bcl2 family: regulators of the cellular life-or-death switch

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Cyclophilin-D binding proteins

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Modifications of oxido-reductase activities in adriamycin-resistant leukaemia K562 cells

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Mitochondria as the central control point of apoptosis

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Effect of PSC 833 on the cytotoxicity and pharmacodynamics of mitoxantrone in multidrug-resistant K562 cells.

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Peptidylproline cis/trans isomerases

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Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

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7 January 2021

Alterations in the expression of cytochrome c oxidase subunits in doxorubicin-resistant leukemia K562 cells.

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7 January 2021

The pathophysiology of mitochondrial cell death

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7 January 2021

Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis

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7 January 2021

Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary adenocarcinoma (MTLn3) cells

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7 January 2021

Mitochondria as subcellular targets for clinically useful anthracyclines

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7 January 2021

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

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7 January 2021

Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides.

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7 January 2021

Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis

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7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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The ability of verapamil to restore intracellular accumulation of anthracyclines in multidrug resistant cells depends on the kinetics of their uptake.

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7 January 2021

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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7 January 2021

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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7 January 2021

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

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7 January 2021

Cellular resistance to anthracyclines.

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7 January 2021

Effects of decreasing mitochondrial volume on the regulation of the permeability transition pore

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7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

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7 January 2021

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

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7 January 2021

Mitochondria, the killer organelles and their weapons

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7 January 2021

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

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7 January 2021

A general pattern for substrate recognition by P-glycoprotein.

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7 January 2021

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

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7 January 2021

Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209293

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25 December 2017

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25 December 2017