Redox cycling of Cu(II) by 6-mercaptopurine leads to ROS generation and DNA breakage: possible mechanism of anticancer activity (Q46821737)

25 December 2017

title

Redox cycling of Cu(II) by 6-mercaptopurine leads to ROS generation and DNA breakage: possible mechanism of anticancer activity (English)

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25 December 2017

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Sayeed Ur Rehman

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25 December 2017

Haseeb Zubair

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25 December 2017

Tarique Sarwar

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25 December 2017

Mohammed Amir Husain

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25 December 2017

Hassan Mubarak Ishqi

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25 December 2017

Shamshun Nehar

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25 December 2017

Mohammad Tabish

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25 December 2017

publication date

25 October 2014

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25 December 2017

published in

Tumor Biology

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25 December 2017

volume

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25 December 2017

issue

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25 December 2017

page(s)

1237-1244

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25 December 2017

What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Medical management of crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Use of thiopurines in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

The purine path to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Role of reactive oxygen species in cis-dichlorodiammineplatinum-induced cytotoxicity on bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Oxidative breakage of cellular DNA by plant polyphenols: a putative mechanism for anticancer properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Studies on the mechanism of action of 6-mercaptopurine. Interaction with copper and xanthine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Mitochondrial oxidative stress plays a key role in aging and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Generation of hydrogen peroxide and superoxide anion from active metabolites of naphthylamines and aminoazo dyes: its possible role in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Potassium bromate causes cell lysis and induces oxidative stress in human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

A simple technique for quantitation of low levels of DNA damage in individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

The puzzle posed by COMMD1, a newly discovered protein binding Cu(ii)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Reactive oxygen species, cell signaling, and cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Implication of mitochondria-derived ROS and cardiolipin peroxidation in N-(4-hydroxyphenyl)retinamide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Interaction of Cu2+ ion with milk xanthine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-2743-X

Effects of gamma-linolenic acid, flavonoids, and vitamins on cytotoxicity and lipid peroxidation

21 January 2018

1 reference

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1 reference

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Role of metal-binding in the biological activities of drugs

1 reference

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Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration 1Supported in part by NIH Grant HL58016. The manuscript was not subjected to internal Agency review and, thus, the opinions are those of the

1 reference

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Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis

1 reference

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Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

1 reference

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DNA breakage induced by piceatannol and copper(II): Mechanism and anticancer properties

1 reference

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Imbalance of purine metabolism in hepatomas of different growth rates as expressed in behavior of xanthine oxidase (EC 1.2.3.2)

1 reference

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Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells

1 reference

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Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway

1 reference

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Oxygen radical damage to DNA by rifamycin SV and copper ions

1 reference

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10.1007/S13277-014-2743-X

Identifiers

DOI

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25 December 2017

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25 December 2017