RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling (Q46797029)

25 December 2017

title

RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling (English)

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25 December 2017

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Bruno Canguilhem

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25 December 2017

Anne Pradines

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25 December 2017

Caroline Baudouin

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25 December 2017

Céline Boby

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25 December 2017

Isabelle Lajoie-Mazenc

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25 December 2017

Marie Charveron

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25 December 2017

Gilles Favre

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25 December 2017

language of work or name

English

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publication date

8 November 2005

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25 December 2017

Journal of Biological Chemistry

published in

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25 December 2017

volume

280

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25 December 2017

issue

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25 December 2017

page(s)

43257-43263

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25 December 2017

Molecular basis of sun-induced premature skin ageing and retinoid antagonism.

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Independent contribution of three different pathways to ultraviolet-B-induced apoptosis

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UV-induced signal transduction

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Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes

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Ras and RhoA suppress whereas RhoB enhances cytokine-induced transcription of nitric oxide synthase-2 in human normal liver AKN-1 cells and lung cancer A-549 cells

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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

21 January 2018

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RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

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Actin' up: RhoB in cancer and apoptosis

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Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells

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Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

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Loss of RhoB expression in human lung cancer progression.

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The expression of rho proteins decreases with human brain tumor progression: potential tumor markers

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Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo

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Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

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Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia

21 January 2018

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RhoB mRNA is stabilized by HuR after UV light

21 January 2018

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21 January 2018

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EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation

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Determination of GTP loading on Rho

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Rational siRNA design for RNA interference

21 January 2018

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Cloning of the human RHOB gene promoter: characterization of a VNTR sequence that affects transcriptional activity

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Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element

21 January 2018

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New aspects of the mechanism of DNA fragmentation in apoptosis

21 January 2018

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XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC

21 January 2018

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UV-Induced stabilization of c-fos and other short-lived mRNAs

21 January 2018

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Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase

21 January 2018

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The role of PI 3-kinase in the UVB-induced expression of c-fos

21 January 2018

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RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1.

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RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

21 January 2018

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Farnesylated RhoB inhibits radiation-induced mitotic cell death and controls radiation-induced centrosome overduplication

21 January 2018

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Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.

21 January 2018

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Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.

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21 January 2018

Identifiers

DOI

10.1074/JBC.M508650200

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25 December 2017

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25 December 2017