Methylprednisolone induces preferential and rapid differentiation of CD34+ cord blood precursors toward NK cells. (Q46726059)

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3 January 2020

title

Methylprednisolone induces preferential and rapid differentiation of CD34+ cord blood precursors toward NK cells (English)

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3 January 2020

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3 January 2020

Francesca Cottalasso

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3 January 2020

Lorenzo Moretta

series ordinal

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3 January 2020

Maria Cristina Mingari

series ordinal

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publication date

28 February 2008

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3 January 2020

published in

International Immunology

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volume

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issue

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page(s)

565-575

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Biology of natural killer cells

3 January 2020

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Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells.

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Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

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Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2.

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Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

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IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors

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KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation

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Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors

21 January 2018

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The corticosteroid-induced inhibitory effect on NK cell function reflects down-regulation and/or dysfunction of triggering receptors involved in natural cytotoxicity.

21 January 2018

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Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells

21 January 2018

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21 January 2018

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21 January 2018

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Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/INTIMM/DXN014

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3 January 2020

1 reference

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