A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine (Q46725875)

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English	A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

1

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Annamaria Vezzani

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Annamaria Vezzani

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24 December 2017

author name string

Giovanna Guiso

2

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Massimo Rizzi

3

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Susanne Pirker

4

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Klaus Novak

5

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Thomas Czech

6

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Christoph Baumgartner

7

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24 December 2017

http://europepmc.org/abstract/MED/16190932

Silvio Caccia

9

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24 December 2017

http://europepmc.org/abstract/MED/16190932

publication date

1 October 2005

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24 December 2017

http://europepmc.org/abstract/MED/16190932

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

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24 December 2017

http://europepmc.org/abstract/MED/16190932

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PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

1613-1619

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PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Recommendations on the clinical use of oxcarbazepine in the treatment of epilepsy: a consensus view

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Mechanisms of antiepileptic drug resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Clinical aspects and biological bases of drug-resistant epilepsies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Vascular and Parenchymal Mechanisms in Multiple Drug Resistance: a Lesson from Human Epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

MDR1 gene expression in brain of patients with medically intractable epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Significance of MDR1 and multiple drug resistance in refractory human epileptic brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

P-glycoprotein-mediated efflux of antiepileptic drugs: preliminary studies in mdr1a knockout mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Multidrug-resistance protein 1 in focal cortical dysplasia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: focal cortical dysplasia and glioneuronal tumors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Relationship between expression of multiple drug resistance proteins and p53 tumor suppressor gene proteins in human brain astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Comparison of mechanisms responsible for resistance to idarubicin and daunorubicin in multidrug resistant LoVo cell lines.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Carbamazepine is not a substrate for P-glycoprotein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Lack of effects of prolonged treatment with phenobarbital or phenytoin on the expression of P-glycoprotein in various rat brain regions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

A novel mechanism underlying drug resistance in chronic epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.00265.X

21 January 2018

Identifiers

10.1111/J.1528-1167.2005.00265.X

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16190932

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