Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS. (Q46703048)

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English	Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS.	scientific article

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PubMed publication ID

16162478

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24 December 2017

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http://europepmc.org/abstract/MED/16162478

title

Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS. (English)

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16162478

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24 December 2017

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main subject

AIDS

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patient

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author

Martin G. Pomper

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Martin G Pomper

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16162478

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Dima A Hammoud

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1

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16162478

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Christopher J Endres

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2

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16162478

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Ankit R Chander

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3

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16162478

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Tomas R Guilarte

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4

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16162478

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Dean F Wong

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5

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16162478

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Ned C Sacktor

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6

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16162478

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Justin C McArthur

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7

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16162478

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publication date

1 August 2005

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16162478

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published in

Journal of NeuroVirology

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16162478

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24 December 2017

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http://europepmc.org/abstract/MED/16162478

volume

11

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16162478

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24 December 2017

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http://europepmc.org/abstract/MED/16162478

issue

4

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16162478

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24 December 2017

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http://europepmc.org/abstract/MED/16162478

page(s)

346-355

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16162478

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24 December 2017

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http://europepmc.org/abstract/MED/16162478

cites work

Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesion

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Visualising microglial activation in vivo

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Immunohistochemical localization of human and simian immunodeficiency viral antigens in fixed tissue sections

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Performance characteristics of a whole-body PET scanner

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Basal ganglia metabolite abnormalities in minor motor disorders associated with human immunodeficiency virus type 1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1.

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12 December 2020

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Human immunodeficiency virus-associated dementia: an evolving disease

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12 December 2020

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Unique monocyte subset in patients with AIDS dementia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Regional pattern of increased omega 3 (peripheral type benzodiazepine) binding site densities in the rat brain induced by systemic injection of kainic acid

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

based on heuristic

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In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

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12 December 2020

based on heuristic

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PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization

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12 December 2020

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The biomedical imaging resource at Mayo Clinic.

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12 December 2020

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[11C](R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Human immunodeficiency virus-infected macrophages, gp120, and N-methyl-D-aspartate receptor-mediated neurotoxicity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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In-vivo measurement of activated microglia in dementia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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PET imaging of brain macrophages using the peripheral benzodiazepine receptor in a macaque model of neuroAIDS

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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PET of peripheral benzodiazepine binding sites in the microgliosis of Alzheimer's disease.

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force

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12 December 2020

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Platelet-activating factor production by human fetal microglia. Effect of lipopolysaccharides and tumor necrosis factor-alpha.

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12 December 2020

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Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage

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12 December 2020

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Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study.

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Quinolinic acid production is related to macrophage tropic isolates of HIV-1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Redistribution of HIV outside the lymphoid system with onset of AIDS.

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12 December 2020

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In vivo binding to peripheral benzodiazepine binding sites in lesioned rat brain: comparison between [3H]PK11195 and [18F]PK14105 as markers for neuronal damage

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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HIV infection and dementia

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Elevated peripheral benzodiazepine receptor expression in simian immunodeficiency virus encephalitis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

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HIV-1 Envelope Glycoprotein 120 Regulates Brain IL-1 β System and TNF- α mRNAs In Vivo

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Semiquantification of the peripheral-type benzodiazepine ligand [11C]PK11195 in normal human brain and application in multiple sclerosis patients

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195.

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PubMed

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Frequency and topographical distribution of CD68-positive macrophages and HIV-1 core proteins in HIV-associated brain lesions.

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12 December 2020

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Column-switching HPLC for the analysis of plasma in PET imaging studies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

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Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

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Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection

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12 December 2020

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A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Regional and temporal expression of the peripheral benzodiazepine receptor in MPTP neurotoxicity

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12 December 2020

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PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia

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https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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Insights into the role of immune activation in HIV neuropathogenesis

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

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Increased glial metabolites predict increased working memory network activation in HIV brain injury

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathways to neuronal damage and apoptosis in human immunodeficiency virus type 1-associated dementia: Chemokine receptors, excitotoxicity, and beyond

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

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Microglia in human immunodeficiency virus-associated neurodegeneration.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

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PET visualization of microglia in multiple sclerosis patients using [11C]PK11195

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/16162478

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

DOI

10.1080/13550280500187351

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16162478

retrieved

24 December 2017

reference URL

http://europepmc.org/abstract/MED/16162478

Dimensions Publication ID

1028725707

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PubMed publication ID

16162478

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16162478

retrieved

24 December 2017

reference URL

http://europepmc.org/abstract/MED/16162478

 

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