Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction (Q46675845)

24 December 2017

title

Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction (English)

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24 December 2017

author name string

Guang-hao Zhang

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24 December 2017

Min Chao

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24 December 2017

Long-hua Hui

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24 December 2017

Dong Ling Xu

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24 December 2017

We-li Cai

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24 December 2017

Jie Zheng

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24 December 2017

Min Gao

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24 December 2017

Ming-xiang Zhang

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24 December 2017

Juan Wang

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24 December 2017

Qing-hua Lu

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24 December 2017

publication date

31 August 2015

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24 December 2017

Clinical and Experimental Pharmacology and Physiology

published in

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24 December 2017

volume

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issue

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24 December 2017

page(s)

1266-1274

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24 December 2017

Aging: a theory based on free radical and radiation chemistry

cites work

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DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

21 January 2018

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Poly(ADP-ribose) polymerase activation by reactive nitrogen species--relevance for the pathogenesis of inflammation

21 January 2018

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Nitric oxide-dependent negative feedback of PARP-1 trans-activation of the inducible nitric-oxide synthase gene

21 January 2018

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Atherosclerosis and the two faces of endothelial nitric oxide synthase

21 January 2018

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Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells.

21 January 2018

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PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats.

21 January 2018

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Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme

21 January 2018

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Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

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Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation

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21 January 2018

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Inflammation and endothelial dysfunction during aging: role of NF-kappaB

21 January 2018

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Arginase: a critical regulator of nitric oxide synthesis and vascular function

21 January 2018

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Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction

21 January 2018

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Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

21 January 2018

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Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function

21 January 2018

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21 January 2018

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Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

21 January 2018

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Diabetes-induced coronary vascular dysfunction involves increased arginase activity

21 January 2018

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Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways.

21 January 2018

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Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway

21 January 2018

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Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity

21 January 2018

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Motif module map reveals enforcement of aging by continual NF-kappaB activity

21 January 2018

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A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation

21 January 2018

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

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Inhibition of high-mobility group box 1 improves myocardial fibrosis and dysfunction in diabetic cardiomyopathy

21 January 2018

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A meprin inhibitor suppresses atherosclerotic plaque formation in ApoE-/- mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/1440-1681.12484

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24 December 2017

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24 December 2017