Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes (Q46643735)

23 December 2017

title

Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes (English)

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23 December 2017

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Subhadra C. Gunawardana

object named as

Subhadra C Gunawardana

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W Steven Head

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23 December 2017

David W Piston

series ordinal

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23 December 2017

publication date

15 April 2008

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23 December 2017

American Journal of Physiology - Endocrinology and Metabolism

published in

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23 December 2017

volume

294

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23 December 2017

issue

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23 December 2017

page(s)

E1097-108

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23 December 2017

Studies on pyrazinoylguanidine. 2. Comparative drug and dose effects on glucose and lipid metabolism in streptozotocin-induced diabetic rats

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Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice

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Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets

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Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH

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Intracellular pH plays a critical role in glucose-induced time-dependent potentiation of insulin release in rat islets

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Timing of Ca2+ response in pancreatic beta-cells is related to mitochondrial mass

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Comparison of the effects of Ca2+, adenine nucleotides and pH on the kinetic properties of mitochondrial NAD(+)-isocitrate dehydrogenase and oxoglutarate dehydrogenase from the yeast Saccharomyces cerevisiae and rat heart

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Newer aspects of glutamine/glutamate metabolism: the role of acute pH changes

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Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate

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Stimulus-secretion coupling in beta-cells: modulation by pH

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Glucose-stimulated signaling pathways in biphasic insulin secretion

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-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels

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Role of phosphoinositide metabolism in induction of memory in isolated perifused rat islets.

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12 December 2020

Different dynamics of insulin secretion in the perfused pancreas of mouse and rat

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12 December 2020

Correction of diabetic pattern of insulin release from islets of the spiny mouse (Acomys cahirinus) by glucose priming in vitro

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12 December 2020

Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats

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12 December 2020

Potentiation of insulin release by glucose in man

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12 December 2020

Time and dose dependencies for priming effect of glucose on insulin secretion

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12 December 2020

ATP-sensitive K+ channel closure is not an obligatory step for glucose-induced priming of pancreatic B-cell

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12 December 2020

Modulation by cytosolic pH of calcium and rubidium fluxes in rat pancreatic islets

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12 December 2020

Role of pH as a transduction device in triggering electrical and secretory responses in islet B cells

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12 December 2020

Loss of a priming effect of glucose on A and D cell secretion in perfused pancreases from alloxan-diabetic rats: Role of insulin and alloxan

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12 December 2020

Ketoisocaproic acid and leucine increase cytoplasmic pH in mouse pancreatic B cells: role of cytoplasmic Ca2+ and pH-regulating exchangers

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12 December 2020

Species differences in the induction of time-dependent potentiation of insulin secretion

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12 December 2020

Lack of glucose-induced priming of insulin release in the perfused mouse pancreas

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12 December 2020

Potentiation of insulin release by glucose in man. I. Quantitative analysis of the enhancement of glucose-induced insulin secretion by pretreatment with glucose in normal subjects

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12 December 2020

Na+-H+ exchange in the process of glucose-induced insulin release from the pancreatic B-cell. Effects of amiloride on 86Rb, 45Ca fluxes and insulin release

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12 December 2020

Responsiveness and memory of the pancreatic B-cells to the insulin secretagogues D-glucose and L-arginine in prediabetic and diabetic rabbits

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12 December 2020

Potentiation of insulin release by glucose in man. II. Role of the insulin response, and enhancement of stimuli other than glucose

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12 December 2020

The stimulus-secretion coupling of amino acid-induced insulin release. XI. Kinetics of deamination and transamination reactions

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Studies on pyrazinoylguanidine. 6. Prevention of cataracts in STZ-diabetic rats

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12 December 2020

Time-dependent potentiation of insulin release induced by alpha-ketoisocaproate and leucine in rats: possible involvement of phosphoinositide hydrolysis

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12 December 2020

Altered metabolic priming by D-glucose in pancreatic islets from Goto-Kakizaki rats

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12 December 2020

Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase

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12 December 2020

Influence of pyruvic acid methyl ester on rat pancreatic islets. Effects on insulin secretion, phosphoinositide hydrolysis, and sensitization of the beta cell

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12 December 2020

Nutrient-Induced Priming of Insulin and Glucagon Secretion. Effects of a-Ketoisocaproic Acid*

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12 December 2020

Mechanism of glucose-induced biphasic insulin release: physiological role of adenosine triphosphate-sensitive K+ channel-independent glucose action

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12 December 2020

Suppressing Na+ Influx Induces an Increase in Intracellular ATP Concentration in Mouse Pancreatic .BETA.-Cells

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12 December 2020

Studies on pyrazinoylguanidine. 1. Characterization of metabolic effects in diabetic rats

1 reference

12 December 2020

Measurement of mitochondrial pH in situ

1 reference

12 December 2020

Feed-back inhibition of insulin secretion in subjects with high and low insulin response to glucose

1 reference

12 December 2020

The role of metabolism, cytoplasmic Ca2+, and pH-regulating exchangers in glucose-induced rise of cytoplasmic pH in normal mouse pancreatic islets

1 reference

12 December 2020

10.1152/AJPENDO.00748.2007

Identifiers

DOI

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23 December 2017

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23 December 2017