Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential (Q46581862)

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scientific article published on 22 May 2008

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English	Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential	scientific article published on 22 May 2008

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Europe PubMed Central

PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

title

Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential (English)

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PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

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hypermethylation

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M H Jiang

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1

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Europe PubMed Central

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18496667

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23 December 2017

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J Fei

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2

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18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

M S Lan

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3

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PubMed publication ID

18496667

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23 December 2017

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Z P Lu

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4

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18496667

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M Liu

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5

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18496667

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23 December 2017

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W W Fan

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6

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18496667

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23 December 2017

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X Gao

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7

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Europe PubMed Central

PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

D R Lu

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8

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Europe PubMed Central

PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

publication date

22 May 2008

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18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

published in

Diabetologia

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PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

volume

51

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Europe PubMed Central

PubMed publication ID

18496667

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23 December 2017

reference URL

http://europepmc.org/abstract/MED/18496667

issue

8

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Europe PubMed Central

PubMed publication ID

18496667

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23 December 2017

reference URL

http://europepmc.org/abstract/MED/18496667

page(s)

1525-1533

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PubMed publication ID

18496667

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23 December 2017

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http://europepmc.org/abstract/MED/18496667

cites work

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The role of glucokinase in the phosphorylation of glucose by rat liver

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Identification of valid housekeeping genes and antioxidant enzyme gene expression change in the aging rat liver

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Phosphorylation of glucose in isolated rat hepatocytes. Sigmoidal kinetics explained by the activity of glucokinase alone

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Site-specific methylation of the rat prolactin and growth hormone promoters correlates with gene expression

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Investigation of the role of epigenetic modification of the rat glucokinase gene in fetal programming

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Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors

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Microdetermination of glycogen with anthrone reagent

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Physical activity and aging

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

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An Age-dependent Modification of Enzyme Regulation

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12 December 2020

based on heuristic

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Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter

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12 December 2020

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Insulin resistance as a predictor of age-related diseases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Impact of Insulin Resistance on Risk of Type 2 Diabetes and Cardiovascular Disease in People With Metabolic Syndrome

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12 December 2020

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Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis

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12 December 2020

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Regulation of phosphoenolpyruvate carboxykinase (GTP) synthesis in rat liver cells. Rapid induction of specific mRNA by glucagon or cyclic AMP and permissive effect of dexamethasone

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12 December 2020

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Circadian and age-dependent expression patterns of GLUT2 and glucokinase in the pancreatic beta-cell of diabetic and nondiabetic rats

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Rat glucokinase gene: structure and regulation by insulin

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PubMed

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12 December 2020

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Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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An alternate promoter in the glucokinase gene is active in the pancreatic beta cell

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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The effect of aging on carbohydrate metabolism: A review of the English literature and a practical approach to the diagnosis of diabetes mellitus in the elderly

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12 December 2020

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Glucose 6-Phosphate Produced by Glucokinase, but Not Hexokinase I, Promotes the Activation of Hepatic Glycogen Synthase

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

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Effect of 5-azacytidine and congeners on DNA methylation and expression of deoxycytidine kinase in the human lymphoid cell lines CCRF/CEM/0 and CCRF/CEM/dCk-1.

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12 December 2020

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Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

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INSULIN-DEPENDENT SYNTHESIS OF LIVER GLUCOKINASE IN THE RAT

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine methylation: quantitation by automated genomic sequencing and GENESCAN analysis.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction of diabetic alterations by glucokinase.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two methods for the determination of glycogen in liver

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

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12 December 2020

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Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream

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12 December 2020

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Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression

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Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

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Characterization of the insulin resistance of aging

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Epstein-Barr virus (EBV) in endemic Burkitt's lymphoma: molecular analysis of primary tumor tissue.

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Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

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12 December 2020

based on heuristic

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Liver glucokinase: decreased activity in patients with type II diabetes

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12 December 2020

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Insulin resistance, beta-cell function, and glucose tolerance in Brazilian adolescents with obesity or risk factors for type 2 diabetes mellitus

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose 6-phosphate produced by gluconeogenesis and by glucokinase is equally effective in activating hepatic glycogen synthase

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose administration induces the premature expression of liver glucokinase gene in newborn rats. Relation with DNase-I-hypersensitive sites

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging, adiposity, and calorie restriction

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18496667

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12 December 2020

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Identifiers

DOI

10.1007/S00125-008-1034-8

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Europe PubMed Central

PubMed publication ID

18496667

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18496667

PubMed publication ID

18496667

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18496667

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18496667

ResearchGate publication ID

5352873

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