Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans (Q46438870)

22 December 2017

title

Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans (English)

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22 December 2017

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Chun-Su Yuan

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22 December 2017

Harold Doshan

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22 December 2017

Martha R Charney

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22 December 2017

Michael O'connor

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22 December 2017

Theodore Karrison

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22 December 2017

S A Maleckar

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22 December 2017

Robert J Israel

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22 December 2017

Jonathan Moss

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22 December 2017

publication date

1 May 2005

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22 December 2017

The Journal of Clinical Pharmacology

published in

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22 December 2017

volume

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22 December 2017

issue

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22 December 2017

page(s)

538-546

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22 December 2017

The use of quaternary narcotic antagonists in opiate research

cites work

1 reference

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Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: a double-blind randomized placebo-controlled trial

21 January 2018

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The safety and efficacy of oral methylnaltrexone in preventing morphine-induced delay in oral-cecal transit time

21 January 2018

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Effects of enteric-coated methylnaltrexone in preventing opioid-induced delay in oral-cecal transit time

21 January 2018

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Effects of subcutaneous methylnaltrexone on morphine-induced peripherally mediated side effects: a double-blind randomized placebo-controlled trial

21 January 2018

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Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial.

21 January 2018

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Efficacy of orally administered methylnaltrexone in decreasing subjective effects after intravenous morphine

21 January 2018

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Opioid-induced delay in gastric emptying: a peripheral mechanism in humans

21 January 2018

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Oral methylnaltrexone for opioid-induced constipation

21 January 2018

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Selective postoperative inhibition of gastrointestinal opioid receptors

21 January 2018

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Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test

21 January 2018

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Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbable carbohydrate

21 January 2018

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Safety and tolerance of methylnaltrexone in healthy humans: a randomized, placebo-controlled, intravenous, ascending-dose, pharmacokinetic study

21 January 2018

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The current status of opioid research on gastrointestinal motility

21 January 2018

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The central and peripheral influences of opioids on gastrointestinal propulsion

21 January 2018

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Opioid antagonists: a review of their role in palliative care, focusing on use in opioid-related constipation

21 January 2018

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Insights into opioid action in the intestinal tract

21 January 2018

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Oral morphine in chronic cancer pain

21 January 2018

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Unrecognized constipation in patients with advanced cancer: a recipe for therapeutic disaster

21 January 2018

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Naloxone, a specific opioid antagonist, reverses chronic idiopathic constipation

21 January 2018

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Naloxone treatment for irritable bowel syndrome--a randomized controlled trial with an oral formulation

21 January 2018

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Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine

21 January 2018

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Gastric effects of methylnaltrexone on mu, kappa, and delta opioid agonists induced brainstem unitary responses

21 January 2018

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Anxiety and pain: attentional and endorphinergic influences

21 January 2018

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Non-specific effect of naltrexone on ethanol consumption in social drinkers

21 January 2018

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Opioid antagonists for smoking cessation.

21 January 2018

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Naltrexone does not block the subjective effects of oral Delta(9)-tetrahydrocannabinol in humans

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1177/0091270004273491

1 reference

22 December 2017

release_5tdqlcyy6zgcjaeswonzmoj47y

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5tdqlcyy6zgcjaeswonzmoj47y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

22 December 2017