Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy (Q46434108)

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scientific article published on 12 August 2008

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English	Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy	scientific article published on 12 August 2008

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Europe PubMed Central

PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

title

Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy (English)

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PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

main subject

non-small-cell lung carcinoma

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Stuart Thomson

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1

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18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

Filippo Petti

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2

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18696232

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22 December 2017

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Izabela Sujka-Kwok

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3

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18696232

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22 December 2017

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David Epstein

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4

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18696232

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22 December 2017

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John D Haley

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5

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PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

publication date

12 August 2008

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18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

published in

Clinical & Experimental Metastasis

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Europe PubMed Central

PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

volume

25

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Europe PubMed Central

PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

issue

8

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Europe PubMed Central

PubMed publication ID

18696232

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22 December 2017

reference URL

http://europepmc.org/abstract/MED/18696232

page(s)

843-854

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PubMed publication ID

18696232

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22 December 2017

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http://europepmc.org/abstract/MED/18696232

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Convenient and versatile subcellular extraction procedure, that facilitates classical protein expression profiling and functional protein analysis

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PubMed

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12 December 2020

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Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra

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PubMed

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12 December 2020

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Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Reporting protein identification data: the next generation of guidelines.

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

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12 December 2020

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Frequent down-regulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas

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12 December 2020

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Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth

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12 December 2020

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

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12 December 2020

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A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451.

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Expression profiling of epithelial plasticity in tumor progression

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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inferred from PubMed ID database lookup

Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Molecular correlates of gefitinib responsiveness in human bladder cancer cells

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12 December 2020

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Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930.

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Cancer metastasis: building a framework

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12 December 2020

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Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells

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12 December 2020

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Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

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12 December 2020

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Identification and prognostic significance of an epithelial-mesenchymal transition expression profile in human bladder tumors

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https://pubmed.ncbi.nlm.nih.gov/18696232

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New signals from the invasive front

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Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

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Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

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https://pubmed.ncbi.nlm.nih.gov/18696232

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A causal role for E-cadherin in the transition from adenoma to carcinoma

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PubMed

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

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PubMed

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Targets of fibroblast growth factor 1 (FGF-1) and FGF-2 signaling involved in the invasive and tumorigenic behavior of carcinoma cells

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Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity

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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

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Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

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PubMed

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Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling

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Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer

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Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

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https://pubmed.ncbi.nlm.nih.gov/18696232

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Autocrine PDGFR signaling promotes mammary cancer metastasis

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12 December 2020

based on heuristic

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OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

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Snail blocks the cell cycle and confers resistance to cell death

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12 December 2020

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The transcriptional repressor Snail promotes mammary tumor recurrence

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial-mesenchymal transitions in tumour progression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18696232

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12 December 2020

based on heuristic

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Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition

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https://pubmed.ncbi.nlm.nih.gov/18696232

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Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

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Identifiers

DOI

10.1007/S10585-008-9200-4

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Europe PubMed Central

PubMed publication ID

18696232

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18696232

PubMed publication ID

18696232

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18696232

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18696232

ResearchGate publication ID

23164822

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