Decreased M1 muscarinic receptor density in rat amphetamine model of schizophrenia is normalized by clozapine, but not haloperidol (Q46354616)

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scientific article published on 20 September 2008

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English	Decreased M1 muscarinic receptor density in rat amphetamine model of schizophrenia is normalized by clozapine, but not haloperidol	scientific article published on 20 September 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

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http://europepmc.org/abstract/MED/18806925

title

Decreased M1 muscarinic receptor density in rat amphetamine model of schizophrenia is normalized by clozapine, but not haloperidol (English)

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

main subject

schizophrenia

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author

Abraham Weizman

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2

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Abraham Weizman

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Europe PubMed Central

PubMed publication ID

18806925

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21 December 2017

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http://europepmc.org/abstract/MED/18806925

author name string

Adi Malkoff

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1

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PubMed publication ID

18806925

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21 December 2017

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http://europepmc.org/abstract/MED/18806925

Illana Gozes

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3

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Europe PubMed Central

PubMed publication ID

18806925

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21 December 2017

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http://europepmc.org/abstract/MED/18806925

Moshe Rehavi

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4

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PubMed publication ID

18806925

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21 December 2017

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http://europepmc.org/abstract/MED/18806925

publication date

20 September 2008

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Europe PubMed Central

PubMed publication ID

18806925

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21 December 2017

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http://europepmc.org/abstract/MED/18806925

published in

Journal of Neural Transmission

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

volume

115

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

issue

11

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

page(s)

1563-1571

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Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

cites work

Antibodies against cerebral M1 cholinergic muscarinic receptor from schizophrenic patients: molecular interaction

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21 January 2018

Low muscarinic receptor binding in prefrontal cortex from subjects with schizophrenia: a study of Brodmann's areas 8, 9, 10, and 46 and the effects of neuroleptic drug treatment

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21 January 2018

Antischizophrenic drugs and brain cholinergic receptors. Affinity for muscarinic sites predicts extrapyramidal effects

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21 January 2018

Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia

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21 January 2018

Autoradiographic analysis of regional alterations in brain receptors following chronic administration and withdrawal of typical and atypical neuroleptics in rats

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Muscarinic1 and 2 receptor mRNA in the human caudate-putamen: no change in m1 mRNA in schizophrenia.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Neurotransmitters, receptors and neuropeptides in post-mortem brains of chronic schizophrenic patients.

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Scopolamine induces disruption of latent inhibition which is prevented by antipsychotic drugs and an acetylcholinesterase inhibitor.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Towards a muscarinic hypothesis of schizophrenia.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dopamine D2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic d-amphetamine on social behavior of the rat: implications for an animal model of paranoid schizophrenia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Chronic treatment with first or second generation antipsychotics in rodents: effects on high affinity nicotinic and muscarinic acetylcholine receptors in the brain

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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In vivo olanzapine occupancy of muscarinic acetylcholine receptors in patients with schizophrenia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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inferred from PubMed ID database lookup

The binding of [3H]AF-DX 384 is reduced in the caudate-putamen of subjects with schizophrenia

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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inferred from PubMed ID database lookup

5-HT2A and muscarinic receptors in schizophrenia: a postmortem study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physostigmine and lithium response in the schizophrenias

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain neurotransmitter receptors after long-term haloperidol: Dopamine, acetylcholine, serotonin, α-noradrenergic and naloxone receptors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Latent inhibition, but not prepulse inhibition, is reduced during withdrawal from an escalating dosage schedule of amphetamine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A putative animal model of the "prodromal" state of schizophrenia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3h]pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rat cerebral cortex

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol and clozapine antagonise amphetamine-induced disruption of latent inhibition of conditioned taste aversion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopaminergic and Cholinergic Interaction in Cataleptic Responses in Mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of glucose-regulated protein 78 in colon cancer.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased muscarinic cholinergic receptors in prefrontal cortices of medicated schizophrenics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphetamine-sensitized animals show a sensorimotor gating and neurochemical abnormality similar to that of schizophrenia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of m1/m4 muscarinic receptors in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression disorder

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-desmethylclozapine, a major metabolite of clozapine, increases cortical acetylcholine and dopamine release in vivo via stimulation of M1 muscarinic receptors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central muscarinic acetylcholine receptor availability in patients treated with clozapine

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of muscarinic receptors in schizophrenia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic administration of neuroleptic and anticholinergic agents on densities of D2 dopamine and muscarinic cholinergic receptors in rat striatum.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

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Serum Levels of Anticholinergic Drugs in Treatment of Acute Extrapyramidal Side Effects

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic receptors as a target for drugs treating schizophrenia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of agonist binding to putative muscarinic subtypes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. II. Characterization and regulation of antagonist binding to putative muscarinic subtypes.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

retrieved

12 December 2020

based on heuristic

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Searching for schizophrenia genes

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18806925

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00702-008-0122-8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

PubMed publication ID

18806925

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18806925

retrieved

21 December 2017

reference URL

http://europepmc.org/abstract/MED/18806925

 

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