Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease (Q46233748)

20 December 2017

title

Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease (English)

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20 December 2017

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20 December 2017

Jessie Theuns

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20 December 2017

Sebastiaan Engelborghs

Sebastiaan Engelborghs

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20 December 2017

Joke Reumers

Joke Reumers

Christine Van Broeckhoven

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Christine Van Broeckhoven

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20 December 2017

Peter Paul De Deyn

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20 December 2017

Patrick Cras

Patrick Cras

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20 December 2017

Veerle Bogaerts

Veerle Bogaerts

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20 December 2017

Barbara A Pickut

Barbara Pickut

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20 December 2017

Ellen Corsmit

Ellen Corsmit

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20 December 2017

Karen Nuytemans

Karen Nuytemans

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20 December 2017

Philippe Pals

Philippe Pals

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20 December 2017

author name string

Karin Peeters

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20 December 2017

Frederic Rousseau

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20 December 2017

publication date

1 June 2008

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20 December 2017

published in

Human Mutation

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20 December 2017

volume

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20 December 2017

issue

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20 December 2017

page(s)

832-840

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20 December 2017

Sequence variants in SLITRK1 are associated with Tourette's syndrome

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Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

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Tissue-specific splicing of Omi stress-regulated endoprotease leads to an inactive protease with a modified PDZ motif

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

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Metallothionein gene expression is regulated by serum factors and activators of protein kinase C

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Oxidative stress in Parkinson's disease

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Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

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Mitochondrial import of Omi: the definitive role of the putative transmembrane region and multiple processing sites in the amino-terminal segment

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7 January 2021

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

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7 January 2021

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

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7 January 2021

Mitochondria in Parkinson disease: back in fashion with a little help from genetics

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7 January 2021

Automated splicing mutation analysis by information theory

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7 January 2021

Mitochondrial involvement in Parkinson's disease

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The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

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7 January 2021

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7 January 2021

Apoptosis in Parkinson's disease: signals for neuronal degradation

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7 January 2021

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7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1002/HUMU.20713

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20 December 2017

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20 December 2017