Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour. (Q46204187)

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English	Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour.	scientific article

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Anna-Britta Lind

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Finn Bengtsson

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Michele Jonzier-Perey

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kerry Powell Golay

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Johan Ahlner

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Pierre Baumann

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Marja-Liisa Dahl

8

1 reference

Europe PubMed Central

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18 January 2020

publication date

1 January 2009

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18 January 2020

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

48

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Europe PubMed Central

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18 January 2020

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

63-70

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19071885%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene

1 reference

https://api.crossref.org/works/10.2165%2F0003088-200948010-00005

21 January 2018

Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism

1 reference

https://api.crossref.org/works/10.2165%2F0003088-200948010-00005

21 January 2018

Population pharmacokinetic analysis of mirtazapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolism of mirtazapine enantiomers by human cytochrome P450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PET neuroimaging of [11C]mirtazapine enantiomers in pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 IA2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of mirtazapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical relevance of preclinical data: mirtazapine, a model compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mirtazapine enantiomers in blood and cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mirtazapine naturalistic depression study (in Sweden)--MINDS(S): clinical efficacy and safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytochrome P-448 iso-enzymes and related glucuronyltransferases in the human liver by cigarette smoking

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of Mirtazapine: Enantioselective Effects of the CYP2D6 Ultra Rapid Metabolizer Genotype and Correlation with Adverse Effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and biotransformation of mirtazapine in human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chirality in the new generation of antidepressants: stereoselective analysis of the enantiomers of mirtazapine, N-demethylmirtazapine, and 8-hydroxymirtazapine by LC-MS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro studies of induction and inhibition of drug oxidation in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic Drug Monitoring of Mirtazapine, Desmethylmirtazapine, 8-Hydroxymirtazapine, and Mirtazapine-N-oxide by Enantioselective HPLC With Fluorescence Detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19071885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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