Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. (Q46110235)

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scientific article published on 6 March 2008

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English	Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.	scientific article published on 6 March 2008

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3 January 2020

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia (English)

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3 January 2020

Stuart M. Brierley

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3 January 2020

Ashley Blackshaw

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3 January 2020

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Walter E B Sipe

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3 January 2020

Christopher M Martin

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3 January 2020

Benjamin D Phillis

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3 January 2020

Francisco Bautista Cruz

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3 January 2020

Eileen F Grady

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3 January 2020

Wolfgang Liedtke

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3 January 2020

David M Cohen

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3 January 2020

Stephen Vanner

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3 January 2020

Nigel W Bunnett

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3 January 2020

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6 March 2008

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3 January 2020

American Journal of Physiology - Gastrointestinal and Liver Physiology

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3 January 2020

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3 January 2020

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3 January 2020

G1288-98

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3 January 2020

A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator

1 reference

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Hypotonicity induces TRPV4-mediated nociception in rat.

1 reference

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21 January 2018

Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Activation of splanchnic and pelvic colonic afferents by bradykinin in mice

1 reference

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21 January 2018

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Role for protease activity in visceral pain in irritable bowel syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability

1 reference

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21 January 2018

TRP channels as cellular sensors

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Activation and sensitisation of the vanilloid receptor: role in gastrointestinal inflammation and function

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Cutaneous and colonic rat DRG neurons differ with respect to both baseline and PGE2-induced changes in passive and active electrophysiological properties

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Quantitative assessment and characterization of visceral nociception and hyperalgesia in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Mechanisms of protease-activated receptor 2-evoked hyperexcitability of nociceptive neurons innervating the mouse colon

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation

1 reference

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21 January 2018

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

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Abnormal osmotic regulation in trpv4 -/- mice

1 reference

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Altered rectal perception is a biological marker of patients with irritable bowel syndrome.

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TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons

1 reference

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21 January 2018

Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism

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21 January 2018

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2.

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Proteinase-activated receptors, targets for kallikrein signaling

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Protease-activated receptors: contribution to physiology and disease

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Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function

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Hypotonic cell swelling induces translocation of the alpha isoform of cytosolic phospholipase A2 but not the gamma isoform in Ehrlich ascites tumor cells

1 reference

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21 January 2018

Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2008

21 January 2018

Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling

1 reference

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Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice

1 reference

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Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

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Impaired Pressure Sensation in Mice Lacking TRPV4

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Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives

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Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels

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Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum

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Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress

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21 January 2018

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