T cell killing does not require the formation of a stable mature immunological synapse. (Q46039675)

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scientific article published on 28 March 2004

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English	T cell killing does not require the formation of a stable mature immunological synapse.	scientific article published on 28 March 2004

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Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

title

T cell killing does not require the formation of a stable mature immunological synapse. (English)

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Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

main subject

immunology

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author name string

Marco A Purbhoo

series ordinal

1

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Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

Darrell J Irvine

series ordinal

2

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Europe PubMed Central

PubMed publication ID

15048111

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18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

Johannes B Huppa

series ordinal

3

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Europe PubMed Central

PubMed publication ID

15048111

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18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

Mark M Davis

series ordinal

4

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stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

language of work or name

English

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publication date

28 March 2004

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Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

published in

Nature Immunology

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stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

volume

5

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Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

issue

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

page(s)

524-530

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

cites work

The immunological synapse.

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7 January 2021

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Information transfer at the immunological synapse.

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Dynamics of Cell Surface Molecules During T Cell Recognition

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Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells

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The minimal number of class II MHC-antigen complexes needed for T cell activation

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Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

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Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

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Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies

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Minimal requirements for peptide mediated activation of CD8+ CTL.

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Direct observation of ligand recognition by T cells.

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Three-dimensional segregation of supramolecular activation clusters in T cells

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The immunological synapse: a molecular machine controlling T cell activation

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Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

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Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

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7 January 2021

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An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

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Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes

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The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.

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Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

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Do T cell receptors do it alone?

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7 January 2021

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Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells

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Differential clustering of CD4 and CD3zeta during T cell recognition

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A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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Quantitating protein synthesis, degradation, and endogenous antigen processing

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Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing

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7 January 2021

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Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.

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A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

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Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

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7 January 2021

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The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

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Comparison of Fas- versus perforin-mediated pathways of cytotoxicity in TCR- and Thy-1-activated murine T cells

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Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

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Continuous T cell receptor signaling required for synapse maintenance and full effector potential

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TCR-Mediated internalization of peptide-MHC complexes acquired by T cells

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The immunological synapse of CTL contains a secretory domain and membrane bridges.

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Production of high-titer helper-free retroviruses by transient transfection

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Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

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Identifiers

DOI

10.1038/NI1058

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

PubMed publication ID

15048111

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15048111

retrieved

18 December 2017

reference URL

http://europepmc.org/abstract/MED/15048111

ResearchGate publication ID

8652942

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