The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. (Q46028223)

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scientific article published in May 1997

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English	The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy.	scientific article published in May 1997

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

author name string

Ramirez MT

1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Sah VP

2

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Zhao XL

3

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Hunter JJ

4

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Chien KR

5

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Brown JH

6

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

language of work or name

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publication date

1 May 1997

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

272

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

22

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

14057-14061

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Activation of c-Jun-NH2-kinase by UV irradiation is dependent on p21ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.22.14057

21 January 2018

Identifiers

10.1074/JBC.272.22.14057

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/9162028

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