Overexpression of aldehyde dehydrogenase-2 attenuates neurotoxicity induced by 4-hydroxynonenal in cultured primary hippocampal neurons. (Q46018306)

18 December 2017

title

Overexpression of aldehyde dehydrogenase-2 attenuates neurotoxicity induced by 4-hydroxynonenal in cultured primary hippocampal neurons. (English)

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18 December 2017

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Jing Bai

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18 December 2017

Yuanwu Mei

series ordinal

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18 December 2017

publication date

2 April 2010

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18 December 2017

published in

Neurotoxicity Research

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18 December 2017

volume

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18 December 2017

issue

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18 December 2017

page(s)

412-422

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18 December 2017

Biochemical pathways of caspase activation during apoptosis

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Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

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Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase

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12 December 2020

4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells

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12 December 2020

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease

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12 December 2020

Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases

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12 December 2020

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide

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12 December 2020

Lipid peroxidation products and antioxidants in human disease

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12 December 2020

The lipid peroxidation by-product 4-hydroxynonenal is toxic to axons and oligodendrocytes

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12 December 2020

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

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12 December 2020

Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues.

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12 December 2020

Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells

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12 December 2020

Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system

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12 December 2020

10.1007/S12640-010-9183-1

Identifiers

DOI

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18 December 2017

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18 December 2017