Pharmacogenetic impact of VKORC1 and CYP2C9 allelic variants on warfarin dose requirements in a hispanic population isolate. (Q45945749)

18 December 2017

title

Pharmacogenetic impact of VKORC1 and CYP2C9 allelic variants on warfarin dose requirements in a hispanic population isolate. (English)

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18 December 2017

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Mauricio Arcos-Burgos

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18 December 2017

author name string

Lina Palacio

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18 December 2017

Diana Falla

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18 December 2017

Ignacio Tobon

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18 December 2017

Fernando Mejia

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18 December 2017

John E Lewis

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18 December 2017

Ariel F Martinez

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18 December 2017

Mauricio Camargo

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18 December 2017

publication date

29 June 2009

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18 December 2017

Clinical and Applied Thrombosis-Hemostasis

published in

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18 December 2017

volume

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18 December 2017

issue

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18 December 2017

page(s)

83-90

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18 December 2017

Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

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Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

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Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients.

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Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations

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A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

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Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

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The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

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21 January 2018

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Vitamin K supplementation can improve stability of anticoagulation for patients with unexplained variability in response to warfarin.

21 January 2018

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VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.

21 January 2018

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Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/1076029608330472

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18 December 2017

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18 December 2017