Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer. (Q45882718)

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20 January 2020

title

Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer (English)

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20 January 2020

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20 January 2020

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20 January 2020

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20 January 2020

K Birkholz

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20 January 2020

A Hombach

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20 January 2020

C Krug

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20 January 2020

S Reuter

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20 January 2020

E Kämpgen

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20 January 2020

G Schuler

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20 January 2020

H Abken

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20 January 2020

publication date

22 January 2009

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20 January 2020

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20 January 2020

volume

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20 January 2020

issue

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20 January 2020

page(s)

596-604

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Cancer despite immunosurveillance: immunoselection and immunosubversion

20 January 2020

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A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer

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A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells

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Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/GT.2008.189

1 reference

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Dimensions Publication ID

20 January 2020

1023978429

0 references

1 reference

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