Toward development of a non-viral gene therapeutic (Q45868146)

17 December 2017

title

Toward development of a non-viral gene therapeutic (English)

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17 December 2017

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Niven R

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17 December 2017

Zhang Y

series ordinal

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17 December 2017

Smith J

series ordinal

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17 December 2017

language of work or name

English

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publication date

1 July 1997

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17 December 2017

Advanced Drug Delivery Reviews

published in

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17 December 2017

volume

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17 December 2017

issue

2-3

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17 December 2017

page(s)

135-150

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17 December 2017

Splicing and the formation of stable RNA

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Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

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Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

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Transformation-dependent expression of interleukin genes delivered by a recombinant parvovirus

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High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

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Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules

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Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

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Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans

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Immunotherapy of malignancy by in vivo gene transfer into tumors

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7 January 2021

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

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7 January 2021

Transfer of genes to humans: early lessons and obstacles to success

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7 January 2021

Liposomes as agents of DNA transfer

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7 January 2021

Gene Transfer In Vivo with DNA–Liposome Complexes: Safety and Acute Toxicity in Mice

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7 January 2021

Cationic liposome-mediated intravenous gene delivery

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7 January 2021

Non-viral gene therapy

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7 January 2021

Cationic liposome-mediated transfection.

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7 January 2021

Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle

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7 January 2021

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

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7 January 2021

Transfection of adherent murine peritoneal macrophages with a reporter gene using DEAE-dextran

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7 January 2021

The influence of sodium glycocholate and other additives on the in vivo transfection of plasmid DNA in the lungs

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7 January 2021

DNA packaging induced by micellar aggregates: a novel in vitro DNA condensation system

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7 January 2021

Microencapsulation of DNA within alginate microspheres and crosslinked chitosan membranes for in vivo application

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Direct gene transfer into mouse muscle in vivo

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Stability and Properties of Double and Triple Helices: Dramatic Effects of RNA or DNA Backbone Composition

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7 January 2021

Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles

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7 January 2021

In vitro and in vivo gene transfer to pulmonary cells mediated by cationic liposomes.

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7 January 2021

Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.

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7 January 2021

Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Converting an alcohol to an amine in a cationic lipid dramatically alters the co-lipid requirement, cellular transfection activity and the ultrastructure of DNA-cytofectin complexes

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Improvements in cationic liposomes for in vivo gene transfer

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Large unilamellar liposomes with low uptake into the reticuloendothelial system

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors

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7 January 2021

Biodistribution and immunotargetability of ganglioside-stabilized dioleoylphosphatidylethanolamine liposomes

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7 January 2021

Dehydration-induced lamellar-to-hexagonal-II phase transitions in DOPE/DOPC mixtures

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7 January 2021

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

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7 January 2021

Fusion of cationic liposomes with mammalian cells occurs after endocytosis

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7 January 2021

Liposomes for the transformation of eukaryotic cells

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7 January 2021

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

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7 January 2021

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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7 January 2021

Potentiation of cationic liposome-mediated gene delivery by polycations

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7 January 2021

Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

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7 January 2021

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action

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7 January 2021

High-efficiency transfection of primary human keratinocytes with positively charged lipopolyamine:DNA complexes.

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7 January 2021

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Thermodynamic stability theory for DNA doughnut shapes induced by charge neutralization.

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7 January 2021

Counterion-induced condensation of deoxyribonucleic acid. A light-scattering study

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7 January 2021

Condensation of DNA by trivalent cations. 1. Effects of DNA length and topology on the size and shape of condensed particles

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7 January 2021

The compaction of DNA helices into either continuous supercoils or folded-fiber rods and toroids

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Measurement of the pH of Frozen Buffer Solutions by Using pH Indicators

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Formation of stable cationic lipid/DNA complexes for gene transfer

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Comparative study of capillary zone electrophoresis and high-performance liquid chromatography in the analysis of oligonucleotides and DNA

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Promises and problems of biological atomic force microscopy

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7 January 2021

Some problems of zeta potential determination in electrophoretic measurements on lipid membranes

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7 January 2021

NMR studies of drug-DNA complexes.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Circular dichroism spectroscopy of DNA

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection

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7 January 2021

Nonspecific ligand-DNA equilibrium binding parameters determined by fluorescence methods.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Time-resolved and equilibrium measurements of the effects of poly(ethylene glycol) on small unilamellar phospholipid vesicles

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7 January 2021

Gene therapy advances slowly into the clinic

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7 January 2021

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

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7 January 2021

Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses

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7 January 2021

Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoprotein-polylysine carriers

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7 January 2021

Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression

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7 January 2021

Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle

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7 January 2021

Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake

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7 January 2021

Galactosylated histone-mediated gene transfer and expression

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7 January 2021

Transferrin-polycation conjugates as carriers for DNA uptake into cells

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7 January 2021

DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety

1 reference

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7 January 2021

Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells

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7 January 2021

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle

1 reference

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7 January 2021

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes

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7 January 2021

Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes

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7 January 2021

Highly efficient transfection into primary cultured mouse hepatocytes by use of cation-liposomes: an application for immunization

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7 January 2021

Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

Mechanisms of nuclear protein import.

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7 January 2021

Cytoplasmic expression of a reporter gene by co-delivery of T7 RNA polymerase and T7 promoter sequence with cationic liposomes

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7 January 2021

Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

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7 January 2021

Structural and functional organization of the nuclear envelope.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

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https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900031-8

7 January 2021

10.1016/S0169-409X(97)00031-8

Identifiers

DOI

1 reference

17 December 2017

1 reference

17 December 2017