Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer (Q45857062)

17 December 2017

title

Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer (English)

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17 December 2017

author name string

M Perro

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17 December 2017

J Tsang

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17 December 2017

S-A Xue

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17 December 2017

D Escors

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17 December 2017

M Cesco-Gaspere

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17 December 2017

C Pospori

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17 December 2017

L Gao

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17 December 2017

D Hart

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17 December 2017

M Collins

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17 December 2017

H Stauss

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17 December 2017

E C Morris

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17 December 2017

publication date

18 February 2010

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

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17 December 2017

issue

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17 December 2017

page(s)

721-732

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17 December 2017

Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation

cites work

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

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Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy

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Adoptive cellular therapy for early cytomegalovirus infection after allogeneic stem-cell transplantation with virus-specific T-cell lines.

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Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes

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Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

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Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy

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Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

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Lineage relationship and protective immunity of memory CD8 T cell subsets

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

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Adoptive immunotherapy for cancer: building on success

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Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes

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Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the alpha beta TCR complex

21 January 2018

1 reference

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

21 January 2018

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Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes

21 January 2018

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Potentiation of tumor eradication by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells

21 January 2018

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High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

21 January 2018

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Reconstitution of CD8+ T cells by retroviral transfer of the TCR alpha beta-chain genes isolated from a clonally expanded P815-infiltrating lymphocyte.

21 January 2018

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Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

21 January 2018

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A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

21 January 2018

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Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

21 January 2018

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Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

21 January 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

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Lentiviral vectors for T-cell suicide gene therapy: preservation of T-cell effector function after cytokine-mediated transduction

21 January 2018

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Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

21 January 2018

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Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

21 January 2018

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Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells.

21 January 2018

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CD28-mediated co-stimulation: a quantitative support for TCR signalling

21 January 2018

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Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production

21 January 2018

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

21 January 2018

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Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

21 January 2018

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Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory act

21 January 2018

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Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes

21 January 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

21 January 2018

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Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.

21 January 2018

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IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells.

21 January 2018

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IL-21 influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response

21 January 2018

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

21 January 2018

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

21 January 2018

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T-cell quality in memory and protection: implications for vaccine design

21 January 2018

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Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE).

21 January 2018

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Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

21 January 2018

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7 January 2021

Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

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7 January 2021

Immunotherapy through TCR gene transfer

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7 January 2021

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

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7 January 2021

Identifiers

DOI

10.1038/GT.2010.4

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17 December 2017

Dimensions Publication ID

1049070060

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1 reference

17 December 2017