PTEN regulates matrix synthesis in adult human chondrocytes under oxidative stress (Q45834365)

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English	PTEN regulates matrix synthesis in adult human chondrocytes under oxidative stress	scientific article

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Europe PubMed Central

PubMed publication ID

24155249

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16 December 2017

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http://europepmc.org/abstract/MED/24155249

title

PTEN regulates matrix synthesis in adult human chondrocytes under oxidative stress (English)

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24155249

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16 December 2017

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author name string

Kenjiro Iwasa

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1

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24155249

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16 December 2017

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Shinya Hayashi

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2

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24155249

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16 December 2017

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Takaaki Fujishiro

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3

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24155249

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16 December 2017

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Noriyuki Kanzaki

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4

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24155249

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Shingo Hashimoto

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5

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24155249

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Shuhei Sakata

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6

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24155249

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16 December 2017

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Nobuaki Chinzei

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7

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24155249

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16 December 2017

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Takayuki Nishiyama

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8

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24155249

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Ryosuke Kuroda

series ordinal

9

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24155249

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16 December 2017

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Masahiro Kurosaka

series ordinal

10

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24155249

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16 December 2017

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publication date

24 October 2013

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24155249

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16 December 2017

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published in

Journal of Orthopaedic Research

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24155249

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16 December 2017

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http://europepmc.org/abstract/MED/24155249

volume

32

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24155249

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16 December 2017

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http://europepmc.org/abstract/MED/24155249

issue

2

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24155249

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16 December 2017

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http://europepmc.org/abstract/MED/24155249

page(s)

231-237

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24155249

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cites work

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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Crossref

reference URL

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retrieved

21 January 2018

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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21 January 2018

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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21 January 2018

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

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21 January 2018

PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.

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21 January 2018

IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways

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21 January 2018

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation--divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation.

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21 January 2018

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

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21 January 2018

PTEN and inherited hamartoma-cancer syndromes

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21 January 2018

Mutations of PTEN in patients with Bannayan-Riley-Ruvalcaba phenotype

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21 January 2018

Pten is essential for embryonic development and tumour suppression

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21 January 2018

Conditional loss of PTEN leads to skeletal abnormalities and lipoma formation.

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21 January 2018

Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth

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Crossref

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21 January 2018

Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels

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21 January 2018

Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function

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21 January 2018

The presence of molecular markers of in vivo lipid peroxidation in osteoarthritic cartilage: a pathogenic role in osteoarthritis

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21 January 2018

Extracellular superoxide dismutase and oxidant damage in osteoarthritis.

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21 January 2018

Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways

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21 January 2018

IGF-I stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI 3-kinase pathway but not ERK MAPK.

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21 January 2018

Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells.

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21 January 2018

Mechanism of tert-butylhydroperoxide induced cytotoxicity in U-937 macrophages by alteration of mitochondrial function and generation of ROS.

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21 January 2018

Role of the phosphatase PTEN in early vascular remodeling.

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21 January 2018

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

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21 January 2018

Identifiers

DOI

10.1002/JOR.22506

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24155249

retrieved

16 December 2017

reference URL

http://europepmc.org/abstract/MED/24155249

PubMed publication ID

24155249

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24155249

retrieved

16 December 2017

reference URL

http://europepmc.org/abstract/MED/24155249

 

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