Wild-type huntingtin protects neurons from excitotoxicity (Q45299841)

11 December 2017

title

Wild-type huntingtin protects neurons from excitotoxicity (English)

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11 December 2017

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11 December 2017

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11 December 2017

Blair R Leavitt

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11 December 2017

Cheryl L Wellington

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11 December 2017

Rona K Graham

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11 December 2017

Jeremy M Van Raamsdonk

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object named as

Jeremy M van Raamsdonk

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11 December 2017

Jacqueline Shehadeh

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11 December 2017

Herman Fernandes

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11 December 2017

Zoe Murphy

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11 December 2017

language of work or name

English

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publication date

17 January 2006

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Journal of Neurochemistry

11 December 2017

published in

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11 December 2017

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11 December 2017

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11 December 2017

page(s)

1121-1129

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The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin

11 December 2017

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Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

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Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease

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Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

21 January 2018

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Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene

21 January 2018

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Inhibition of ICE slows ALS in mice

21 January 2018

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10.1111/J.1471-4159.2005.03605.X

21 January 2018

Identifiers

DOI

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11 December 2017

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