Tissue-specific aberrations of gene expression in HPRT-deficient mice: functional complexity in a monogenic disease? (Q45224300)

11 December 2017

title

Tissue-specific aberrations of gene expression in HPRT-deficient mice: functional complexity in a monogenic disease? (English)

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11 December 2017

Theodore Friedmann

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11 December 2017

Shaochun Song

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11 December 2017

publication date

15 May 2007

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11 December 2017

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11 December 2017

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11 December 2017

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11 December 2017

page(s)

1432-1443

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Inherited disorder of purine metabolism. Correlation between central nervous system dysfunction and biochemical defects

11 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency in Gout

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Lesch-Nyhan syndrome and its pathogenesis: purine concentrations in plasma and urine with metabolite profiles in CSF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Self-injury in Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Determination of the mutations responsible for the Lesch-Nyhan syndrome in 17 subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

The spectrum of inherited mutations causing HPRT deficiency: 75 new cases and a review of 196 previously reported cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Biochemical Evidence of Dysfunction of Brain Neurotransmitters in the Lesch-Nyhan Syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Monoamine Oxidase Activity Decreased in Cells Lacking Hypoxanthine Phosphoribosyltransferase Activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Lesch-Nyhan syndrome: CSF neurotransmitter abnormalities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Evidence that lack of brain dopamine during development can increase the susceptibility for aggression and self-injurious behavior by influencing D1-dopamine receptor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Lesch-Nyhan syndrome: a study of motor behavior and cerebrospinal fluid neurotransmitters.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Presynaptic dopaminergic deficits in Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Impaired differentiation of HPRT-deficient dopaminergic neurons: a possible mechanism underlying neuronal dysfunction in Lesch-Nyhan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Neonatal-6-hydroxydopamine treatment: model of susceptibility for self-mutilation in the Lesch-Nyhan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Effects of adult or neonatal treatment with 6-hydroxydopamine or 5,7-dihydroxytryptamine on locomotor activity, monoamine levels, and response to caffeine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Analysis of forebrain dopaminergic pathways in HPRT-mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Animal models of Lesch-Nyhan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Influence of age and strain on striatal dopamine loss in a genetic mouse model of Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Brain purines in a genetic mouse model of Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Characterization of the dopamine defect in primary cultures of dopaminergic neurons from hypoxanthine phosphoribosyltransferase knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Dopamine metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient variants of PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Gelsolin overexpression enhances neurite outgrowth in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Guanine nucleotide depletion induces differentiation and aberrant neurite outgrowth in human dopaminergic neuroblastoma lines: a model for basal ganglia dysfunction in Lesch-Nyhan disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Study of the adenosinergic system in the brain of HPRT knockout mouse (Lesch-Nyhan disease).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Adenine nucleotide turnover in hypoxanthine-guanine phosphoribosyl-transferase deficiency: evidence for an increased contribution of purine biosynthesis de novo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300199

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300199

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11 December 2017

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