Cartilage tissue formation from dedifferentiated chondrocytes by codelivery of BMP-2 and SOX-9 genes encoding bicistronic vector (Q45207048)

10 December 2017

title

Cartilage tissue formation from dedifferentiated chondrocytes by codelivery of BMP-2 and SOX-9 genes encoding bicistronic vector (English)

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10 December 2017

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Byung-Hyun Cha

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10 December 2017

Jae-Hwan Kim

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10 December 2017

Sun-Woong Kang

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10 December 2017

Hyun-Jin Do

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10 December 2017

Ju-Woong Jang

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10 December 2017

Yon Rak Choi

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10 December 2017

Hansoo Park

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10 December 2017

Byung-Soo Kim

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10 December 2017

Soo-Hong Lee

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10 December 2017

publication date

5 July 2012

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10 December 2017

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10 December 2017

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10 December 2017

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10 December 2017

page(s)

1519-1528

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Sox9 is required for cartilage formation

10 December 2017

cites work

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Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling

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Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation

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The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells

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Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes

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Future perspectives of articular cartilage repair.

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Surface modification with fibrin/hyaluronic acid hydrogel on solid-free form-based scaffolds followed by BMP-2 loading to enhance bone regeneration

21 January 2018

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Targeting of focal adhesion kinase by small interfering RNAs reduces chondrocyte redifferentiation capacity in alginate beads culture with type II collagen.

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Improving chondrogenesis: potential and limitations of SOX9 gene transfer and mechanical stimulation for cartilage tissue engineering.

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Continuous transforming growth factor beta1 secretion by cell-mediated gene therapy maintains chondrocyte redifferentiation

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Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells

21 January 2018

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SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

21 January 2018

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Production of collagens, collagenase and collagenase inhibitor during the dedifferentiation of articular chondrocytes by serial subcultures

21 January 2018

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Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes

21 January 2018

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Redifferentiation of in vitro expanded adult articular chondrocytes by combining the hanging-drop cultivation method with hypoxic environment

21 January 2018

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Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through BMP pathway and a CCAAT box in the proximal promoter

21 January 2018

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Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence

21 January 2018

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Regulation of SOX9 mRNA in human articular chondrocytes involving p38 MAPK activation and mRNA stabilization

21 January 2018

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Responsiveness of bovine chondrocytes to growth factors in medium with different serum concentrations

21 January 2018

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Microporation is a valuable transfection method for gene expression in human adipose tissue-derived stem cells

21 January 2018

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Repair of injured articular and growth plate cartilage using mesenchymal stem cells and chondrogenic gene therapy.

21 January 2018

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Impact of expansion and redifferentiation conditions on chondrogenic capacity of cultured chondrocytes

21 January 2018

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The transcription factor Sox9 is involved in BMP-2 signaling.

21 January 2018

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Parallel expression ofSox9 andCol2a1 in cells undergoing chondrogenesis

21 January 2018

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Human adipose tissue is a source of multipotent stem cells

21 January 2018

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Multilineage cells from human adipose tissue: implications for cell-based therapies

21 January 2018

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Cryopreservation and biophysical properties of articular cartilage chondrocytes

21 January 2018

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Mammalian Chondrocytes Expanded in the Presence of Fibroblast Growth Factor 2 Maintain the Ability to Differentiate and Regenerate Three-Dimensional Cartilaginous Tissue

21 January 2018

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21 January 2018

Identifiers

DOI

10.3727/096368912X647261

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10 December 2017

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