The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity (Q45171657)

10 December 2017

title

The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity (English)

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10 December 2017

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10 December 2017

Benjamin F Cravatt

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10 December 2017

Sachin Patel

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10 December 2017

Erica J Carrier

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10 December 2017

W-S Vanessa Ho

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10 December 2017

David J Rademacher

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10 December 2017

Sonya Cunningham

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10 December 2017

D Sudarshan Reddy

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10 December 2017

Cecilia J Hillard

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10 December 2017

language of work or name

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1 December 2004

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Journal of Lipid Research

10 December 2017

published in

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10 December 2017

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10 December 2017

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10 December 2017

page(s)

342-349

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N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain

10 December 2017

cites work

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Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

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Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh

21 January 2018

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21 January 2018

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21 January 2018

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The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase

21 January 2018

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Reversible Hydrolysis and Synthesis of Anandamide Demonstrated by Recombinant Rat Fatty-Acid Amide Hydrolase

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21 January 2018

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Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo

21 January 2018

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Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme.

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The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine

21 January 2018

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Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes

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Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine

21 January 2018

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cDNA cloning and characterization of A3i, an alternatively spliced rat A3 adenosine receptor variant

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Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death

21 January 2018

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

21 January 2018

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Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271

21 January 2018

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10.1194/JLR.M400377-JLR200

21 January 2018

Identifiers

DOI

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10 December 2017

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