Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using alpha-boranophosphate nucleoside analogs (Q45154601)

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scientific article published on 17 November 2004

Mechanistic Insights into the Suppression of Drug Resistance by Human Immunodeficiency Virus Type 1 Reverse Transcriptase Using α-Boranophosphate Nucleoside Analogs

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English	Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using alpha-boranophosphate nucleoside analogs	scientific article published on 17 November 2004	Mechanistic Insights into the Suppression of Drug Resistance by Human Immunodeficiency Virus Type 1 Reverse Transcriptase Using α-Boranophosphate Nucleoside Analogs

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 December 2017

Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using alpha-boranophosphate nucleoside analogs (English)

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Europe PubMed Central

PubMed publication ID

10 December 2017

8

object named as

Bruno Canard

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Europe PubMed Central

PubMed publication ID

10 December 2017

author name string

Jérôme Deval

1

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Europe PubMed Central

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10 December 2017

Karine Alvarez

2

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Europe PubMed Central

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10 December 2017

Boulbaba Selmi

3

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Europe PubMed Central

PubMed publication ID

10 December 2017

Marielle Bermond

4

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Europe PubMed Central

PubMed publication ID

10 December 2017

Joëlle Boretto

5

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Europe PubMed Central

PubMed publication ID

10 December 2017

Catherine Guerreiro

6

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10 December 2017

Laurence Mulard

7

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10 December 2017

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publication date

17 November 2004

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10 December 2017

Journal of Biological Chemistry

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10 December 2017

280

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10 December 2017

5

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10 December 2017

3838-3846

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10 December 2017

Antiviral drugs: current state of the art.

1 reference

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21 January 2018

Targeting HIV: antiretroviral therapy and development of drug resistance.

1 reference

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21 January 2018

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase

1 reference

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21 January 2018

Direct PCR sequencing with boronated nucleotides

1 reference

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21 January 2018

Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methyl phosphonates.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Boron neutron capture therapy for cancer. Realities and prospects.

1 reference

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21 January 2018

Structural basis for activation of α-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Activation of anti-reverse transcriptase nucleotide analogs by nucleoside diphosphate kinase: improvement by alpha-boranophosphate substitution

1 reference

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21 January 2018

The molecular mechanism of multidrug resistance by the Q151M human immunodeficiency virus type 1 reverse transcriptase and its suppression using alpha-boranophosphate nucleotide analogues

1 reference

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21 January 2018

Structural Studies of a Borane-Modified Phosphate Diester Linkage: Ab Initio Calculations on the Dimethylboranophosphate Anion and the Single-Crystal X-ray Structure of Its Diisopropylammonium Salt

1 reference

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21 January 2018

A new intermolecular interaction: unconventional hydrogen bonds with element-hydride bonds as proton acceptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

An integrated system to study multiply substituted human immunodeficiency virus type 1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

On the fidelity of DNA replication: manganese mutagenesis in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I.

1 reference

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21 January 2018

Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP

1 reference

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21 January 2018

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

1 reference

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21 January 2018

Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations

1 reference

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21 January 2018

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

1 reference

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21 January 2018

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

1 reference

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21 January 2018

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP

1 reference

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21 January 2018

Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

1 reference

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21 January 2018

Formation of phosphonester bonds catalyzed by DNA polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

3'-Azido-3',5'-dideoxythymidine-5'-methylphosphonic acid diphosphate: synthesis and HIV-1 reverse transcriptase inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411559200

21 January 2018

Identifiers

10.1074/JBC.M411559200

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

ResearchGate publication ID

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