Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease (Q45146825)

10 December 2017

title

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease (English)

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10 December 2017

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10 December 2017

Gen Sobue

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10 December 2017

Qiang Qiang

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10 December 2017

Zhe Huang

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10 December 2017

Yue-Mei Jiang

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10 December 2017

Masahisa Katsuno

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10 December 2017

Makoto Minamiyama

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10 December 2017

Hideki Doi

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10 December 2017

Shinjiro Matsumoto

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10 December 2017

Naohide Kondo

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10 December 2017

Yu Miyazaki

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10 December 2017

Madoka Iida

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10 December 2017

Genki Tohnai

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10 December 2017

language of work or name

English

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publication date

27 February 2013

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Journal of Neurochemistry

10 December 2017

published in

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10 December 2017

volume

126

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10 December 2017

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10 December 2017

page(s)

122-130

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Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death

10 December 2017

cites work

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Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients

21 January 2018

1 reference

Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy.

21 January 2018

1 reference

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

21 January 2018

1 reference

Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

21 January 2018

1 reference

The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process

21 January 2018

1 reference

Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial.

21 January 2018

1 reference

Androgen Receptor (AR) Coregulators: An Overview

21 January 2018

1 reference

Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer

21 January 2018

1 reference

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait

21 January 2018

1 reference

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

1 reference

Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death

21 January 2018

1 reference

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

21 January 2018

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Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

21 January 2018

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Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease

21 January 2018

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Subchronic and chronic safety studies with genistein in dogs

21 January 2018

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Acute, subchronic and chronic safety studies with genistein in rats

21 January 2018

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Trinucleotide Repeat Disorders

21 January 2018

1 reference

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Neurotoxic effects of androgens in spinal and bulbar muscular atrophy.

21 January 2018

1 reference

Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer

21 January 2018

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Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy

21 January 2018

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17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

21 January 2018

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Genistein is neuroprotective in murine models of familial amyotrophic lateral sclerosis and stroke

21 January 2018

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Concurrent measurement of unbound genistein in the blood, brain and bile of anesthetized rats using microdialysis and its pharmacokinetic application

21 January 2018

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

21 January 2018

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ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

21 January 2018

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Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

21 January 2018

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From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.12172

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10 December 2017

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