Therapeutic effects of a new lymphocyte homing reagent FTY720 in interleukin-10 gene-deficient mice with colitis (Q45004851)

8 December 2017

title

Therapeutic effects of a new lymphocyte homing reagent FTY720 in interleukin-10 gene-deficient mice with colitis (English)

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8 December 2017

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Tsunekazu Mizushima

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8 December 2017

Toshinori Ito

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8 December 2017

Daisuke Kishi

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8 December 2017

Yasuyuki Kai

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8 December 2017

Hiroshi Tamagawa

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8 December 2017

Riichiro Nezu

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8 December 2017

Hiroshi Kiyono

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8 December 2017

Hikaru Matsuda

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8 December 2017

language of work or name

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1 May 2004

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Inflammatory Bowel Diseases

8 December 2017

published in

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8 December 2017

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8 December 2017

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8 December 2017

page(s)

182-192

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Inflammatory Bowel Disease

8 December 2017

cites work

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Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

21 January 2018

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Simple compounds, 2-alkyl-2-amino-1,3-propanediols have potent immunosuppressive activity

21 January 2018

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FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines

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Interleukin-10-deficient mice develop chronic enterocolitis

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gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

21 January 2018

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Alteration of interleukin 4 production results in the inhibition of T helper type 2 cell-dominated inflammatory bowel disease in T cell receptor alpha chain-deficient mice

21 January 2018

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Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells

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T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

21 January 2018

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Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

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Mucosal immune network in the gut for the control of infectious diseases

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Natalizumab for active Crohn's disease

21 January 2018

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Sphingosine 1-phosphate signalling in mammalian cells

21 January 2018

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

21 January 2018

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

21 January 2018

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Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice

21 January 2018

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Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat

21 January 2018

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Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720

21 January 2018

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10.1097/00054725-200405000-00002

21 January 2018

Identifiers

DOI

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8 December 2017

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