Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin (Q44991444)

8 December 2017

title

Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin (English)

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8 December 2017

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Lloyd R Whitfield

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8 December 2017

Anthony R Porcari

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8 December 2017

Christine Alvey

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8 December 2017

Robert Abel

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8 December 2017

William Bullen

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8 December 2017

Daniel Hartman

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8 December 2017

publication date

22 April 2010

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The Journal of Clinical Pharmacology

8 December 2017

published in

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8 December 2017

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8 December 2017

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8 December 2017

page(s)

378-388

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Effective use of combination lipid therapy

8 December 2017

cites work

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https://api.crossref.org/works/10.1177%2F0091270010366446

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270010366446

Gemfibrozil greatly increases plasma concentrations of cerivastatin

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270010366446

Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270010366446

Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270010366446

The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270010366446

Pharmacokinetics of the combination of fluvastatin and gemfibrozil

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270010366446

Simvastatin does not have a clinically significant pharmacokinetic interaction with fenofibrate in humans

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270010366446

An open-label, randomized, three-way crossover trial of the effects of coadministration of rosuvastatin and fenofibrate on the pharmacokinetic properties of rosuvastatin and fenofibric acid in healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270010366446

Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270010366446

An open-label, crossover study of the pharmacokinetics of Insoluble Drug Delivery-MicroParticle fenofibrate in combination with atorvastatin, simvastatin, and extended-release niacin in healthy volunteers

21 January 2018

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Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization

21 January 2018

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effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers

21 January 2018

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Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

21 January 2018

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P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice

21 January 2018

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ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.

21 January 2018

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Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport

21 January 2018

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Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin

21 January 2018

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Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.

21 January 2018

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Effects of fibrates on metabolism of statins in human hepatocytes

21 January 2018

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Efficacy and safety of ABT-335 (fenofibric acid) in combination with atorvastatin in patients with mixed dyslipidemia

21 January 2018

1 reference

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Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0091270010366446

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8 December 2017

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