Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major (Q44999040)

8 December 2017

title

Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major (English)

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8 December 2017

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Leishmania major

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8 December 2017

Esther von Stebut

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8 December 2017

Markus F Neurath

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8 December 2017

Richard S Blumberg

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8 December 2017

Mark Birkenbach

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8 December 2017

Sabine Zahn

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8 December 2017

language of work or name

English

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publication date

1 April 2005

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European Journal of Immunology

8 December 2017

published in

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8 December 2017

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8 December 2017

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8 December 2017

page(s)

1106-1112

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

8 December 2017

cites work

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https://api.crossref.org/works/10.1002%2FEJI.200425926

Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection.

21 January 2018

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WSX-1: a key role in induction of chronic intestinal nematode infection

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

Understanding the pro- and anti-inflammatory properties of IL-27.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425926

CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

IL-12 is required to maintain a Th1 response during Leishmania major infection.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

The regulation of immunity to Leishmania major

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

The immunology of susceptibility and resistance to Leishmania major in mice

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

CD4+ T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Expression of IL-27 in human Th1-associated granulomatous diseases

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Interferon-beta differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Novel IL-12 family members shed light on the orchestration of Th1 responses

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

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https://api.crossref.org/works/10.1002%2FEJI.200425926

7 January 2021

Identifiers

DOI

10.1002/EJI.200425926

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8 December 2017

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