Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing. (Q44930829)

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29 December 2019

title

Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing (English)

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29 December 2019

0 references

1 reference

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29 December 2019

Go Tomiyoshi

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29 December 2019

Yuji Horita

series ordinal

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29 December 2019

Michiru Nishita

series ordinal

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29 December 2019

Kensaku Mizuno

series ordinal

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29 December 2019

publication date

1 June 2004

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29 December 2019

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29 December 2019

volume

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29 December 2019

issue

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29 December 2019

page(s)

591-600

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LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

29 December 2019

cites work

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

21 January 2018

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Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

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Programmed cell death in animal development

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Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

21 January 2018

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Active and inactive protein kinases: structural basis for regulation

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Bleb formation and F-actin distribution during mitosis and tumor necrosis factor-induced apoptosis

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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

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Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis

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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

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Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation

21 January 2018

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The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.

21 January 2018

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Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

21 January 2018

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Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

21 January 2018

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Alterations of the actin polymerization status as an apoptotic morphological effector in HL-60 cells

21 January 2018

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Caspases: Intracellular Signaling by Proteolysis

21 January 2018

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Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

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Proteolytic activation of PKN by caspase-3 or related protease during apoptosis

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21 January 2018

Caspases: enemies within

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation

21 January 2018

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Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells

21 January 2018

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

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Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

21 January 2018

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Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo

21 January 2018

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