Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions (Q44904812)

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English	Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions	scientific article

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Europe PubMed Central

PubMed publication ID

7 December 2017

Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions (English)

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Europe PubMed Central

PubMed publication ID

7 December 2017

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Helen A Seow

1

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7 December 2017

Philip G Penketh

2

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7 December 2017

Michael F Belcourt

3

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7 December 2017

Maria Tomasz

4

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7 December 2017

Sara Rockwell

5

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7 December 2017

Alan C Sartorelli

6

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7 December 2017

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publication date

20 May 2004

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7 December 2017

Journal of Biological Chemistry

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7 December 2017

279

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7 December 2017

30

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7 December 2017

31606-31612

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7 December 2017

The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

MITOMYCINS AND PORFIROMYCIN: CHEMICAL MECHANISM OF ACTIVATION AND CROSS-LINKING OF DNA.

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Metabolic activation of mitomycin C by NADPH-ferredoxin reductase in vitro

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Inhibition of DNA cross-linking by mitomycin C by peroxidase-mediated oxidation of mitomycin C hydroquinone

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Nuclear overexpression of NADH:cytochrome b5 reductase activity increases the cytotoxicity of mitomycin C (MC) and the total number of MC-DNA adducts in Chinese hamster ovary cells

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Nuclear targeting sequences--a consensus?

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

A short amino acid sequence able to specify nuclear location

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

An NLS is sufficient to engage facilitated translocation by the nuclear pore complex and subsequent intranuclear binding

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

The nucleotide sequence of a rat vascular smooth muscle alpha-actin cDNA

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Measurement of protein using bicinchoninic acid

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https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404910200

21 January 2018

Identifiers

10.1074/JBC.M404910200

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Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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