Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition (Q44846041)

6 December 2017

title

Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition (English)

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6 December 2017

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6 December 2017

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6 December 2017

Marcus F Keep

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6 December 2017

Roland Månsson

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6 December 2017

Gustav Mattiasson

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6 December 2017

Jonas Ohlsson

series ordinal

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6 December 2017

Jenny Karlsson

series ordinal

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6 December 2017

language of work or name

English

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publication date

1 May 2004

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Journal of Neurochemistry

6 December 2017

published in

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6 December 2017

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6 December 2017

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6 December 2017

page(s)

715-729

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Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver

6 December 2017

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The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain

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Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia

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Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability

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Mitochondrial permeability transition can be directly monitored in living neurons

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Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

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Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart

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Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria

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Intrathecal cyclosporin prolongs survival of late-stage ALS mice

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Biochemical characterization of the mitochondrial permeability transition in isolated forebrain mitochondria

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Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion

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Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury

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The mitochondrial death/life regulator in apoptosis and necrosis

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The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

21 January 2018

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Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia

21 January 2018

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Cyclosporin A enhances survival, ameliorates brain damage, and prevents secondary mitochondrial dysfunction after a 30-minute period of transient cerebral ischemia

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

21 January 2018

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Dose-response of cyclosporin A in attenuating traumatic axonal injury in rat.

21 January 2018

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Imaging the mitochondrial permeability transition pore in intact cells.

21 January 2018

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Mitochondrial contributions to tissue damage in stroke

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The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury

21 January 2018

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Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury.

21 January 2018

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Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury

21 January 2018

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Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats

21 January 2018

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Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02400.X

Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition

21 January 2018

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21 January 2018

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Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02400.X

Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02400.X

The mitochondrion in apoptosis: how Pandora's box opens

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02400.X

The mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02400.X

10.1111/J.1471-4159.2004.02400.X

21 January 2018

Identifiers

DOI

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6 December 2017

1 reference