Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies (Q44788460)

6 December 2017

title

Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies (English)

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6 December 2017

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Chan-Lan Kim

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6 December 2017

Atsushi Umetani

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6 December 2017

Toshio Matsui

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6 December 2017

Naotaka Ishiguro

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6 December 2017

Morikazu Shinagawa

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6 December 2017

Motohiro Horiuchi

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6 December 2017

language of work or name

English

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publication date

1 March 2004

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6 December 2017

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6 December 2017

volume

320

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6 December 2017

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6 December 2017

page(s)

40-51

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Monoclonal antibodies to the cellular and scrapie prion proteins

6 December 2017

cites work

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Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

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Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state

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Purified prion proteins and scrapie infectivity copartition into liposomes

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Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

7 January 2021

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Synthetic peptide vaccines yield monoclonal antibodies to cellular and pathological prion proteins of ruminants

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A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep

7 January 2021

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Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

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Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change

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Prion (PrPSc)-specific epitope defined by a monoclonal antibody

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Recombinant scrapie-like prion protein of 106 amino acids is soluble

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A prion protein epitope selective for the pathologically misfolded conformation

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A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform 1 1Edited by M. Yaniv

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Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

7 January 2021

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In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies

7 January 2021

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Prion protein expression in different species: analysis with a panel of new mAbs

7 January 2021

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Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

7 January 2021

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Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies.

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Overexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation

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inferred from DOI database lookup

7 January 2021

based on heuristic

Monoclonal antibody F89/160.1.5 defines a conserved epitope on the ruminant prion protein.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2003.10.026

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6 December 2017

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