The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway (Q44652125)

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scientific article published on 10 November 2003

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English	The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway	scientific article published on 10 November 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Thomas Kietzmann

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Ulrike Roth

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Katja Curth

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Terry G Unterman

3

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Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

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publication date

10 November 2003

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Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

5 December 2017

279

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Europe PubMed Central

PubMed publication ID

5 December 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

2623-2631

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Competitive inhibition of liver glucokinase by its regulatory protein

1 reference

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21 January 2018

Mammalian glucokinase and its gene

1 reference

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21 January 2018

Arterial oxygen partial pressures reduce the insulin-dependent induction of the perivenously located glucokinase in rat hepatocyte cultures: mimicry of arterial oxygen pressures by H2O2.

1 reference

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21 January 2018

Zonation of parenchymal and nonparenchymal metabolism in liver

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21 January 2018

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

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Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains

1 reference

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21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Hypoxia-inducible factor 1: control of oxygen homeostasis in health and disease

1 reference

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21 January 2018

Oxygen sensors and angiogenesis

1 reference

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Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

1 reference

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

1 reference

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HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

1 reference

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Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

1 reference

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21 January 2018

Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver

1 reference

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21 January 2018

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

1 reference

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21 January 2018

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

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21 January 2018

Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes

1 reference

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21 January 2018

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

1 reference

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21 January 2018

Identification of upstream stimulatory factor as transcriptional activator of the liver promoter of the glucokinase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes

1 reference

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21 January 2018

Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta

1 reference

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21 January 2018

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer

1 reference

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21 January 2018

The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1.

1 reference

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21 January 2018

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors

1 reference

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21 January 2018

An essential role for p300/CBP in the cellular response to hypoxia

1 reference

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21 January 2018

Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt

1 reference

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21 January 2018

Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

1 reference

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21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

1 reference

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21 January 2018

Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes

1 reference

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21 January 2018

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site

1 reference

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21 January 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

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21 January 2018

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

1 reference

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Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

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Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences

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Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

1 reference

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Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

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Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

1 reference

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Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

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Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

1 reference

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21 January 2018

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

1 reference

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21 January 2018

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308391200

21 January 2018

Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine

1 reference

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21 January 2018

Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein

1 reference

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Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M308391200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

ResearchGate publication ID

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