The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium (Q44612927)

4 December 2017

title

The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium (English)

1 reference

Cardiology and cardiovascular medicine

4 December 2017

main subject

1 reference

DOI

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

20 March 2024

Gentian Kristo

1 reference

4 December 2017

Yukihiro Yoshimura

1 reference

4 December 2017

Jianli Niu

1 reference

4 December 2017

Rolf Bünger

1 reference

4 December 2017

Byron J. Keith

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551043

20 March 2024

Robert M. Mentzer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551043

20 March 2024

Robert D. Lasley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551043

20 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14551043

20 March 2024

publication date

9 October 2003

1 reference

full work available at URL

4 December 2017

https://www.physiology.org/doi/pdf/10.1152/ajpheart.00777.2003

1 reference

DOI

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

American Journal of Physiology Heart and Circulatory Physiology

20 March 2024

published in

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4 December 2017

volume

286

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4 December 2017

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4 December 2017

page(s)

H517-24

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Pyruvate protection against beta-amyloid-induced neuronal death: role of mitochondrial redox state.

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00777.2003

Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state

21 January 2018

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Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure

21 January 2018

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Pyruvate attenuation of hypoxia damage in isolated working guinea-pig heart

21 January 2018

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The influence of lactate, pyruvate and glucose as exogenous substrates on free radical defense mechanisms in isolated rat hearts during ischaemia and reperfusion

21 January 2018

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Influence of pyruvate on contractile performance and Ca(2+) cycling in isolated failing human myocardium

21 January 2018

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Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study

21 January 2018

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Pyruvate potentiates inotropic effects of isoproterenol and Ca(2+) in rabbit cardiac muscle preparations

21 January 2018

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Potentiation of beta-adrenergic inotropic response by pyruvate in failing human myocardium

21 January 2018

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Chemical hypoxia-induced cell death in human glioma cells: role of reactive oxygen species, ATP depletion, mitochondrial damage and Ca2+.

21 January 2018

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Intramitochondrial pyruvate attenuates hydrogen peroxide-induced apoptosis in bovine pulmonary artery endothelium

21 January 2018

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Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization

21 January 2018

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Brief increase in carbohydrate oxidation after reperfusion reverses myocardial stunning in conscious pigs

21 January 2018

1 reference

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Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium

21 January 2018

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Energetic modulation of cardiac inotropism and sarcoplasmic reticular Ca2+ uptake

21 January 2018

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Mitochondrial metabolism of pyruvate is required for its enhancement of cardiac function and energetics

21 January 2018

1 reference

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Pyruvate restores contractile function and antioxidant defenses of hydrogen peroxide-challenged myocardium

21 January 2018

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Effect of pyruvate on regional ventricular function in normal and stunned myocardium.

21 January 2018

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Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00777.2003

Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine

21 January 2018

1 reference

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Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes

21 January 2018

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Production of reactive oxygen by mitochondria from normoxic and hypoxic rat heart tissue

21 January 2018

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Biochemical mechanism of infarct size reduction by pyruvate

21 January 2018

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Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate

21 January 2018

1 reference

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Pyruvate/dichloroacetate supply during reperfusion accelerates recovery of cardiac energetics and improves mechanical function following cardioplegic arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00777.2003

Pyruvate potentiates beta-adrenergic inotropism of stunned guinea-pig myocardium

21 January 2018

1 reference

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Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation

21 January 2018

1 reference

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Cyclic fluctuations in the cardiac performance of the isolated Langendorff-perfused mouse heart: pyruvate abolishes the fluctuations and has an anti-ischaemic effect

21 January 2018

1 reference

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Pyruvate reverses fatty-acid-induced depression of ventricular function and calcium overload after hypothermia in guinea pig hearts

21 January 2018

1 reference

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Inhibitory effect of pyruvate on release of glutathione and swelling of rat heart mitochondria

20 March 2024

1 reference

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The Cumulative Nature of Pyruvate's Dual Mechanism for Myocardial Protection

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Pyruvate improves myocardial tolerance to reperfusion injury by acting as an antioxidant: a chemiluminescence study

20 March 2024

1 reference

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Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species

20 March 2024

1 reference

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Quantification of regional myocardial dysfunction after acute ischemic injury

20 March 2024

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Failure of pyruvate to salvage myocardium after prolonged ischemia

20 March 2024

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Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate

20 March 2024

1 reference

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Protection by pyruvate against transient forebrain ischemia in rats.

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Antioxidant effects of pyruvate in isolated rat hearts

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Pyruvate augments calcium transients and cell shortening in rat ventricular myocytes

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Effects of pyruvate on intracellular Ca2+ regulation in cardiac myocytes from normal and diabetic rats

20 March 2024

1 reference

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Intravenous pyruvate prolongs survival during hemorrhagic shock in swine

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Pyruvate prevents hydrogen peroxide-induced apoptosis

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Pyruvate augments mechanical function via activation of the pyruvate dehydrogenase complex in reperfused ischemic immature rabbit hearts

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Antioxidant properties of pyruvate mediate its potentiation of beta-adrenergic inotropism in stunned myocardium

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

Myocardial stunning: a therapeutic conundrum

20 March 2024

1 reference

https://api.crossref.org/works/10.1152/AJPHEART.00777.2003

20 March 2024

Identifiers

DOI

1 reference

4 December 2017

1 reference