Dimerization of MLL fusion proteins immortalizes hematopoietic cells (Q44615522)

4 December 2017

title

Dimerization of MLL fusion proteins immortalizes hematopoietic cells (English)

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4 December 2017

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4 December 2017

Mary Ellen Martin

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4 December 2017

Sebastien Bloyer

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4 December 2017

Karine Galoian

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4 December 2017

Weiping Shen

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4 December 2017

Denise Gibbs

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4 December 2017

Hugh W Brock

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4 December 2017

Robert Slany

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4 December 2017

Jay L Hess

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4 December 2017

publication date

1 September 2003

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4 December 2017

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4 December 2017

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4 December 2017

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4 December 2017

page(s)

197-207

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Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis

4 December 2017

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

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7 January 2021

The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

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The activity of mammalian brm/SNF2alpha is dependent on a high-mobility-group protein I/Y-like DNA binding domain

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7 January 2021

Complex MLL rearrangement in a patient with T-cell acute lymphoblastic leukemia

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7 January 2021

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

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7 January 2021

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

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7 January 2021

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

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Prognostic significance of partial tandem duplications of the MLL gene in adult patients 16 to 60 years old with acute myeloid leukemia and normal cytogenetics: a study of the Acute Myeloid Leukemia Study Group Ulm.

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Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia

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7 January 2021

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

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Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells

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Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

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7 January 2021

Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes

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7 January 2021

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

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Three-dimensional structure of beta-galactosidase from E. coli

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Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

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7 January 2021

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

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7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

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7 January 2021

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7 January 2021

Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation

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7 January 2021

MLL targets SET domain methyltransferase activity to Hox gene promoters

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7 January 2021

Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice

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7 January 2021

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

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7 January 2021

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

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7 January 2021

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

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7 January 2021

Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

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7 January 2021

Differential gene expression profiling of adult murine hematopoietic stem cells

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7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

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7 January 2021

Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

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7 January 2021

Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia

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7 January 2021

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

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7 January 2021

Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins

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7 January 2021

Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

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7 January 2021

Structure of AF3p21, a new member of mixed lineage leukemia (MLL) fusion partner proteins-implication for MLL-induced leukemogenesis

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7 January 2021

The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator

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Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD

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7 January 2021

MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisom

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7 January 2021

Common mechanism for oncogenic activation of MLL by forkhead family proteins

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7 January 2021

Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes

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7 January 2021

The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21).

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7 January 2021

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia

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7 January 2021

Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion

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7 January 2021

Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments

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7 January 2021

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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7 January 2021

Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties

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7 January 2021

Altered Hox expression and segmental identity in Mll-mutant mice

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7 January 2021

MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis

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7 January 2021

Transcriptional activation is a key function encoded by MLL fusion partners

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900214-9

7 January 2021

10.1016/S1535-6108(03)00214-9

Identifiers

DOI

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release_2caa46iipvgnpjv76faypxysp4

4 December 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/2caa46iipvgnpjv76faypxysp4

24 November 2022

mapped directly with Wikidata item

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