The kynurenine 3-hydroxylase inhibitor Ro 61-8048 improves dystonia in a genetic model of paroxysmal dyskinesia (Q44614711)

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scientific article published on September 30, 2003

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English	The kynurenine 3-hydroxylase inhibitor Ro 61-8048 improves dystonia in a genetic model of paroxysmal dyskinesia	scientific article published on September 30, 2003

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14555184

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4 December 2017

title

The kynurenine 3-hydroxylase inhibitor Ro 61-8048 improves dystonia in a genetic model of paroxysmal dyskinesia (English)

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Europe PubMed Central

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14555184

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4 December 2017

main subject

dyskinesia

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based on heuristic

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animal disease model

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Europe PubMed Central

PubMed publication ID

14555184

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14555184

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pharmacology

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DOI

10.1016/J.EJPHAR.2003.08.038

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https://api.crossref.org/works/10.1016/J.EJPHAR.2003.08.038

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author name string

Angelika Richter

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1

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Europe PubMed Central

PubMed publication ID

14555184

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4 December 2017

Melanie Hamann

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2

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14555184

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4 December 2017

language of work or name

English

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publication date

1 September 2003

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14555184

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4 December 2017

30 September 2003

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National Center for Biotechnology Information

PubMed publication ID

14555184

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14555184

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full work available at URL

https://api.elsevier.com/content/article/PII:S0014299903022738?httpAccept=text/xml

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10.1016/J.EJPHAR.2003.08.038

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https://api.crossref.org/works/10.1016/J.EJPHAR.2003.08.038

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20 March 2024

https://api.elsevier.com/content/article/PII:S0014299903022738?httpAccept=text/plain

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Crossref

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10.1016/J.EJPHAR.2003.08.038

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https://api.crossref.org/works/10.1016/J.EJPHAR.2003.08.038

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published in

European Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

14555184

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4 December 2017

volume

478

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Europe PubMed Central

PubMed publication ID

14555184

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4 December 2017

issue

1

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Europe PubMed Central

PubMed publication ID

14555184

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4 December 2017

page(s)

47-52

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PubMed publication ID

14555184

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cites work

Spontaneous remission of paroxysmal dystonia coincides with normalization of entopeduncular activity in dt(SZ) mutants.

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10.1016/J.EJPHAR.2003.08.038

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Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures

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Quinolinic acid formation in immune-activated mice: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(-3-nitrophenyl)thiazol-2yl]-benzenesul fonamide (Ro 61-8048), two potent and selective inhibitors of kynurenine hydroxylase

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Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia

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Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia

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Deficit of striatal parvalbumin-reactive GABAergic interneurons and decreased basal ganglia output in a genetic rodent model of idiopathic paroxysmal dystonia.

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Abnormalities in amino acid neurotransmitters in discrete brain regions of genetically dystonic hamsters

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The glycine/NMDA receptor ligand (+)-HA-966 but not D-cycloserine has potent antidystonic efficacy in a genetic animal model of dystonia

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The sz mutant hamster: a genetic model of epilepsy or of paroxysmal dystonia?

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Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

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Alterations in N-methyl-D-aspartate receptor binding in dystonic hamster brains

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Changes in AMPA receptor binding in an animal model of inborn paroxysmal dystonia

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Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia

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Pathology of idiopathic dystonia: findings from genetic animal models

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Antidystonic effects of the NMDA receptor antagonists memantine, MK-801 and CGP 37849 in a mutant hamster model of paroxysmal dystonia

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The AMPA receptor antagonist NBQX exerts antidystonic effects in an animal model of idiopathic dystonia

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Increased levels of kynurenic acid in brains of genetically dystonic hamsters

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Antidystonic efficacy of nitric oxide synthase inhibitors in a rodent model of primary paroxysmal dystonia

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Synthesis and Biochemical Evaluation ofN-(4-Phenylthiazol-2-yl)benzenesulfonamides as High-Affinity Inhibitors of Kynurenine 3-Hydroxylase

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Electrophysiological effects of exogenous and endogenous kynurenic acid in the rat brain: studies in vivo and in vitro

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Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

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Kynurenic acid antagonists and kynurenine pathway inhibitors

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Kynurenines in the CNS: from endogenous obscurity to therapeutic importance

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Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors.

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Kynurenine 3-hydroxylase inhibition in rats: effects on extracellular kynurenic acid concentration and N-methyl-D-aspartate-induced depolarisation in the striatum

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Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo

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Identifiers

DOI

10.1016/J.EJPHAR.2003.08.038

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14555184

retrieved

4 December 2017

PubMed publication ID

14555184

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14555184

retrieved

4 December 2017

 

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