Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila (Q44607268)

4 December 2017

title

Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila (English)

1 reference

4 December 2017

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila (English)

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00594-4

18 March 2024

0 references

Shermali Gunawardena

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527431

18 March 2024

Lu-Shiun Her

1 reference

4 December 2017

Beth Gordesky-Gold

1 reference

4 December 2017

Louis Sintasath

1 reference

4 December 2017

Richard G. Brusch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527431

18 March 2024

Robert A. Laymon

1 reference

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18 March 2024

Ingrid R. Niesman

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18 March 2024

Nancy M. Bonini

1 reference

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18 March 2024

Lawrence S. B. Goldstein

1 reference

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18 March 2024

language of work or name

English

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publication date

1 September 2003

1 reference

4 December 2017

25 September 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14527431

full work available at URL

18 March 2024

http://www.cell.com/article/S0896627303005944/pdf

file format

Portable Document Format

online access status

open access

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https://api.elsevier.com/content/article/PII:S0896627303005944?httpAccept=text/xml

18 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00594-4

https://api.elsevier.com/content/article/PII:S0896627303005944?httpAccept=text/plain

18 March 2024

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https://api.crossref.org/works/10.1016/S0896-6273(03)00594-4

18 March 2024

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4 December 2017

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4 December 2017

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4 December 2017

page(s)

25-40

1 reference

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

4 December 2017

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Fast transport and retrograde movement of huntingtin and HAP 1 in axons

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Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein

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A molecular genetic analysis of the interaction between the cytoplasmic dynein intermediate chain and the glued (dynactin) complex

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7 January 2021

Loss of normal huntingtin function: new developments in Huntington's disease research

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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

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Inactivation of the mouse Huntington's disease gene homolog Hdh

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7 January 2021

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

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7 January 2021

Neurodegeneration. A glutamine-rich trail leads to transcription factors

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Mutations in dynein link motor neuron degeneration to defects in retrograde transport

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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

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Abundant expression and cytoplasmic aggregations of [alpha]1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

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7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

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7 January 2021

Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase

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7 January 2021

Interaction of huntingtin-associated protein with dynactin P150Glued

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7 January 2021

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

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7 January 2021

Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

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7 January 2021

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

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Efficient and heritable functional knock-out of an adult phenotype in Drosophila using a GAL4-driven hairpin RNA incorporating a heterologous spacer

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Androgen receptor with elongated polyglutamine tract forms aggregates that alter axonal trafficking and mitochondrial distribution in motor neuronal processes

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Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein

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SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity.

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7 January 2021

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7 January 2021

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

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7 January 2021

Identifiers

1 reference

4 December 2017

1 reference