Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP). (Q44591004)

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scientific article published in January 2003

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English	Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP).	scientific article published in January 2003

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instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

title

Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP) (English)

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

main subject

Alzheimer's disease

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author

Laura A Marlow

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

Kumar Sambamurti

series ordinal

4

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Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

author name string

Melissa Cain

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

Miguel A Pappolla

series ordinal

3

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stated in

Europe PubMed Central

PubMed publication ID

14501002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

publication date

1 January 2003

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

published in

Journal of Molecular Neuroscience

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

volume

20

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

issue

3

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stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

page(s)

233-239

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Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

cites work

An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Framing beta-amyloid

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of lipid rafts in biological membranes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convertases other than furin cleave beta-secretase to its mature form.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of recombinant, soluble beta-secretase from an insect cell expression system.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing and cell biological functions of the amyloid precursor protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/14501002

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1385/JMN:20:3:233

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

Dimensions Publication ID

1004998147

0 references

PubMed publication ID

14501002

1 reference

stated in

Europe PubMed Central

PubMed publication ID

14501002

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14501002%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 December 2019

 

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