MDM2-ARF complex regulates p53 sumoylation (Q44549004)

4 December 2017

title

MDM2-ARF complex regulates p53 sumoylation (English)

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4 December 2017

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Lihong Chen

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4 December 2017

Jiandong Chen

series ordinal

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4 December 2017

language of work or name

English

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publication date

1 August 2003

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4 December 2017

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4 December 2017

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4 December 2017

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4 December 2017

page(s)

5348-5357

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Mapping of the p53 and mdm-2 Interaction Domains

4 December 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Differential regulation of sentrinized proteins by a novel sentrin-specific protease

21 January 2018

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Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

SP-RING for SUMO: new functions bloom for a ubiquitin-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Involvement of PIAS1 in the sumoylation of tumor suppressor p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Functional analysis and intracellular localization of p53 modified by SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Antigen processing by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

SUMO-1 modification activates the transcriptional response of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

21 January 2018

1 reference

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Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

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Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206851

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1206851

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Dimensions Publication ID

4 December 2017

1031516652

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