Evaluation of nonthreshold leukemogenic response to methyl nitrosourea in p53-deficient C3H/He mice (Q44539248)

4 December 2017

title

Evaluation of nonthreshold leukemogenic response to methyl nitrosourea in p53-deficient C3H/He mice (English)

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4 December 2017

Yoko Hirabayashi

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4 December 2017

Kazuko Yoshida

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4 December 2017

Shin-ichi Aizawa

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4 December 2017

Yukio Kodama

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4 December 2017

Jun Kanno

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4 December 2017

Yuji Kurokawa

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4 December 2017

Isao Yoshimura

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4 December 2017

Tohru Inoue

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4 December 2017

publication date

1 August 2003

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Toxicology and Applied Pharmacology

4 December 2017

published in

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4 December 2017

volume

190

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4 December 2017

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4 December 2017

page(s)

251-261

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A new, quantitative, approach to the study of the stages of chemical cartinogenesis in the mouse's skin

4 December 2017

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Hypothetical dose—Response curves for chronic exposures to mutagens or carcinogens subject to simple enzymatic detoxification in the mammalian body

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Possible mechanisms of combination effects in chemical carcinogenesis

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Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent

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The question of thresholds for carcinogenesis

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7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

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New approaches to a definition of threshold values for ?irreversible? toxic effects?

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7 January 2021

Residual toxicity in hematopoietic cells following a single dose of methylnitrosourea

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7 January 2021

Hepatocarcinogenesis in p53-deficient mice

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7 January 2021

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

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7 January 2021

Concepts of threshold in mutagenesis and carcinogenesis

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7 January 2021

Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage.

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7 January 2021

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

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7 January 2021

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

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7 January 2021

Dose-response and threshold-mediated mechanisms in mutagenesis: statistical models and study design

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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Age-associated loss of heterozygosity of tumor suppressor genes in the gastric mucosa of humans.

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7 January 2021

DNA damage and repair: consequences on dose-responses

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7 January 2021

DNA repair: kinetics and thresholds

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7 January 2021

Metabolic detoxification: implications for thresholds.

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7 January 2021

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7 January 2021

DNA adducts: endogenous and induced

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7 January 2021

Current knowledge of mechanisms of carcinogenicity: genotoxins versus non-genotoxins

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7 January 2021

Thresholds in chemical carcinogenesis.

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7 January 2021

Implications of arsenic genotoxicity for dose response of carcinogenic effects

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7 January 2021

Dose-response and threshold effects in cytotoxicity and apoptosis

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7 January 2021

Implication of p53 in base excision DNA repair: in vivo evidence

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7 January 2021

p53 regulation of DNA excision repair pathways

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7 January 2021

The roles of age at treatment and dose in carcinogenesis in C3Hf/Dp mice with a single administration of N-nitroso-N-methylurea

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7 January 2021

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

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7 January 2021

Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background

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7 January 2021

Types and amounts of carcinogens as potential human cancer hazards

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7 January 2021

Mechanistic basis for nonlinearities and thresholds in rat liver carcinogenesis by the DNA-reactive carcinogens 2-acetylaminofluorene and diethylnitrosamine.

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7 January 2021

Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice

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7 January 2021

Stem-cell leukemia: p53 deficiency mediated suppression of leukemic differentiation in C3H/He myeloid leukemia

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7 January 2021

Calorie restriction reduces the incidence of myeloid leukemia induced by a single whole-body radiation in C3H/He mice

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7 January 2021

Nature of leukemic stem cells in murine myelogenous leukemia.

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7 January 2021

Dose-response relationships for carcinogens: a review

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7 January 2021

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Identifiers

DOI

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4 December 2017

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